 | |
| Clinical data | |
|---|---|
| Other names | 5F-AKB-48, 5F-AKB48 |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChemCID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| CompTox Dashboard(EPA) | |
| Chemical and physical data | |
| Formula | C23H30FN3O |
| Molar mass | 383.511 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
5F-APINACA (also known asA-5F-PINACA,[3]5F-AKB-48 or5F-AKB48) is anindazole-basedsynthetic cannabinoid that has been sold online as adesigner drug.[4][5] Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as an example, it is very similar to the correspondingpentanenitrile and 4-chlorobutyl compounds which are claimed as examples 3 and 4.[6]
5F-APINACA was first identified in South Korea.[7] It is expected to be a potentagonist of theCB1 receptor andCB2 receptor.[8] Its metabolism has been described in literature.[9][10][11][12]
5F-APINACA acts as afull agonist with abinding affinity of 1.94 nM atCB1 and 0.266 nM atCB2cannabinoid receptors.[13]
In the United States, 5F-APINACA is aSchedule I controlled substance.[14]
5F-APINACA is anAnlage II controlled drug in Germany since July 2013.
As of October 2015, 5F-APINACA is a controlled substance in China.[15]
5F-APINACA is banned in the Czech Republic.[16]
