William Leonard Pickard has described his experiences with 5-fluoro-AMT, which he hadsynthesized along with6-fluoro-AMT, in personal interviews.[6] According to Pickard, 5-fluoro-AMT had aduration of at minimum 9hours and varied in length significantly.[6] The dose was 25mg and above.[6] Pickard has said that 5-fluoro-AMT was not a "warm drug" but that he remained favorable to it.[6] Its effects includedtime dilation among others.[6] He said that it gave him the worst post-tripheadaches he'd experienced from any psychedelic and they lasted up to 24hours.[6]
Pickard has said that 5-fluoro-AMT is lesspotent and long-lasting than 6-fluoro-AMT.[6] The related drug AMT was one of Pickard's favorite psychedelics, and he said that he took it more than 50times and experienced no negativeside effects with it.[6]
^abcdeNakagawasai O, Arai Y, Satoh SE, Satoh N, Neda M, Hozumi M, Oka R, Hiraga H, Tadano T (January 2004). "Monoamine oxidase and head-twitch response in mice. Mechanisms of alpha-methylated substrate derivatives".Neurotoxicology.25 (1–2):223–232.Bibcode:2004NeuTx..25..223N.doi:10.1016/S0161-813X(03)00101-3.PMID14697897.
^abcdTadano T, Neda M, Hozumi M, Yonezawa A, Arai Y, Fujita T, Kinemuchi H, Kisara K (February 1995). "alpha-Methylated tryptamine derivatives induce a 5-HT receptor-mediated head-twitch response in mice".Neuropharmacology.34 (2):229–234.doi:10.1016/0028-3908(94)00119-d.PMID7617148.
^Kinemuchi H, Arai Y (October 1986). "Selective inhibition of monoamine oxidase A and B by two substrate-analogues, 5-fluoro-alpha-methyltryptamine and p-chloro-beta-methylphenethylamine".Research Communications in Chemical Pathology and Pharmacology.54 (1):125–8.doi:10.1016/0028-3908(91)90057-i.PMID3797802.S2CID34761939.
^Kim SK, Toyoshima Y, Arai Y, Kinemuchi H, Tadano T, Oyama K, et al. (April 1991). "Inhibition of monoamine oxidase by two substrate-analogues, with different preferences for 5-hydroxytryptamine neurons".Neuropharmacology.30 (4):329–35.doi:10.1016/0028-3908(91)90057-i.PMID1852266.S2CID34761939.
^Corne SJ, Pickering RW (1967). "A possible correlation between drug-induced hallucinations in man and a behavioural response in mice".Psychopharmacologia.11 (1):65–78.doi:10.1007/bf00401509.PMID5302272.S2CID3148623.
^Yamamoto T, Ueki S (January 1981). "The role of central serotonergic mechanisms on head-twitch and backward locomotion induced by hallucinogenic drugs".Pharmacology, Biochemistry, and Behavior.14 (1):89–95.doi:10.1016/0091-3057(81)90108-8.PMID6258178.S2CID45561708.
^abWO 2022061242, Baggott M, "Advantageous tryptamine compositions for mental disorders or enhancement", published 2023 March 24, assigned toTactogen
