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| Clinical data | |
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| Other names | 4-TASB; 3-Ethoxy-4-ethylthio-5-methoxyphenethylamine; 3-EtO-4-EtS-5-MeO-PEA |
| Routes of administration | Oral[1][2][3] |
| Drug class | Serotonergic psychedelic;Hallucinogen |
| ATC code |
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| Pharmacokinetic data | |
| Duration of action | 10–15 hours[1] |
| Identifiers | |
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| CAS Number | |
| PubChemCID | |
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| ChEMBL | |
| Chemical and physical data | |
| Formula | C13H21NO2S |
| Molar mass | 255.38 g·mol−1 |
| 3D model (JSmol) | |
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4-Thioasymbescaline (4-TASB), also known as3-ethoxy-4-ethylthio-5-methoxyphenethylamine, is apsychedelic drug of thephenethylamine andscaline families related tomescaline.[1][2][3][4] It is theanalogue ofasymbescaline in which theethoxy group at the 4 position has been replaced with anethylthio group.[1][2][3][4] The drug is one of three possiblethioasymbescaline (TASB)positional isomers, the others being3-thioasymbescaline (3-TASB) and5-thioasymbescaline (5-TASB).[1][2][3][4]
In his bookPiHKAL (Phenethylamines I Have Known and Loved) and other publications,Alexander Shulgin lists 4-TASB's dose as 60 to 100 mgorally and itsduration as 10 to 15 hours.[1] The drug is said to have approximately 4 times thepotency of mescaline.[4][2][3][1]
The effects of 4-TASB have been reported to include "fantasy stuff tomusic", "some jumpy stuff to music", music being "lovely", "pictures not particularly exciting", extremely negativeeyes-closed fantasies while trying tosleep,irritability,agitation,twitchiness, uncomfortableness, feeling disturbed, feeling thatnerve endings are raw and active, possibleneurologicalhyperreflexia, feeling continuouselectrical impulses traveling between nerve endings, continuouserotic arousability seemingly related to thenervous systemoversensitivity, "heartbeat wrongness", "respiration wrongness",water retention,diarrhea, and otherphysicalsymptoms.[1][4] It was described as very intense, as a very threatening material, and one person remarked "DO NOT REPEAT".[1] It was concluded that although 4-TASB had "quite a bit of life", it had more overshadowing physical problems than psychic virtue.[1][4]
Thechemical synthesis of 4-TASB has been described.[1][4]
4-TASB was first described in thescientific literature by Shulgin andPeyton Jacob III in 1984.[4] Subsequently, it was described in greater detail by Shulgin inPiHKAL in 1991.[1]