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| Other names | 4-Fluoromeperidine, 4-Fluoropethidine |
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| Formula | C15H20FNO2 |
| Molar mass | 265.328 g·mol−1 |
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4-Fluoropethidine is a drug that is a derivative ofpethidine (meperidine), which combines pethidine'sopioidanalgesic effects with increasedmonoaminereuptake inhibition. It is around 50% less potent than pethidine as an opioid analgesic, but conversely is 50% more potent as adopamine reuptake inhibitor, with other derivatives such as the 4-iodo and 3,4-dichloro analogues being even more potent dopamine reuptake inhibitors again. However, none of these compounds substitute forcocaine or producestimulant effects in animals, suggesting that they still act primarily as opioid analgesic drugs in practice.[1] Its action and degree of relation to pethidine means that it may be controlled in those countries which have laws about controlled-substance analogues; it is not itself listed in the Controlled Substances Act 1970.[2]
