 | |
| Names | |
|---|---|
| Preferred IUPAC name 4-(Dimethylamino)phenol | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChemSpider |
|
| ECHA InfoCard | 100.009.642 |
| UNII | |
| |
| |
| Properties | |
| C8H11NO | |
| Molar mass | 137.179 g/mol |
| Boiling point | 165 °C (329 °F; 438 K) (0.040 bar) |
| Pharmacology | |
| V03AB27 (WHO) | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
4-Dimethylaminophenol (DMAP) is an aromatic compound containing bothphenol andamine functional groups. It has the molecular formula C8H11NO.
4-Dimethylaminophenol has been used as anantidote forcyanide poisoning.[1] It has also been shown to be effective in treatinghydrogen sulfide toxicity.[2]
It works by generatingmethemoglobin.[3]
This is suitable as an emergency treatment only; treatment must be followed up withsodium thiosulfate orcobalamin.
In an animal model, it has shown effectiveness when givenintramuscularly.[4] Though,intramuscular injection should be avoid due to the probability ofmuscular necrosis after injection.Intravenous injection is recommended in a dose of 250 mg.[5]
