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4-Bromomethcathinone

From Wikipedia, the free encyclopedia
Psychoactive drug and research chemical

Pharmaceutical compound
4-Bromomethcathinone
Legal status
Legal status
Identifiers
  • 1-(4-bromophenyl)-2-(methylamino)propan-1-one
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC10H12BrNO
Molar mass242.116 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • CC(C(=O)C1=CC=C(C=C1)Br)NC
  • InChI=1S/C10H12BrNO/c1-7(12-2)10(13)8-3-5-9(11)6-4-8/h3-7,12H,1-2H3 ☒N
  • Key:OOJXMFNDUXHDOV-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

4-Bromomethcathinone (4-BMC,Brephedrone) is apsychoactive drug andresearch chemical of thephenethylamine,amphetamine, andcathinonechemical classes. It acts as aserotonin-norepinephrine-dopamine releasing agent (SNDRA), and to a lesser degree, as aserotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).[1][2]Cathinones, including 4-BMC, possess neurotoxic and cytotoxic properties.[3]

Legal status

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As of October 2015, 4-BMC is a controlled substance in China.[4]4-Bromomethcathinone is considered a Schedule 1 substance in Virginia.[5]

See also

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References

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  1. ^Bonano JS, Banks ML, Kolanos R, Sakloth F, Barnier ML, Glennon RA, et al. (May 2015)."Quantitative structure-activity relationship analysis of the pharmacology of para-substituted methcathinone analogues".British Journal of Pharmacology.172 (10):2433–2444.doi:10.1111/bph.13030.PMC 4409897.PMID 25438806.
  2. ^Rickli A, Hoener MC, Liechti ME (March 2015). "Monoamine transporter and receptor interaction profiles of novel psychoactive substances: para-halogenated amphetamines and pyrovalerone cathinones".European Neuropsychopharmacology.25 (3):365–376.doi:10.1016/j.euroneuro.2014.12.012.PMID 25624004.
  3. ^Wojcieszak J, Kuczyńska K, Zawilska JB (August 2020)."Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles".Neurotoxicity Research.38 (2):536–551.doi:10.1007/s12640-020-00227-8.PMC 7334283.PMID 32506339.
  4. ^"关于印发《非药用类麻醉药品和精神药品列管办法》的通知" [Notice on the Issuance of the "Regulations on the Listing of Non-pharmaceutical Narcotic Drugs and Psychotropic Drugs"] (in Chinese). China Food and Drug Administration. 27 September 2015. Archived fromthe original on 1 October 2015. Retrieved1 October 2015.
  5. ^"18VAC110-20-322. Placement of Chemicals in Schedule I." Commonwealth of Virginia. 2 December 2015. Retrieved11 March 2016.
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