Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

3-(p-Fluorobenzoyloxy)tropane

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
3-(p-Fluorobenzoyloxy)tropane
Clinical data
Routes of
administration
insufflated
Legal status
Legal status
Identifiers
  • (1R,5S)-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 4-fluorobenzoate
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC15H18FNO2
Molar mass263.312 g·mol−1
3D model (JSmol)
  • CN1C2CC(OC(C3=CC=C(F)C=C3)=O)CC1CC2
  • InChI=1S/C15H18FNO2/c1-17-12-6-7-13(17)9-14(8-12)19-15(18)10-2-4-11(16)5-3-10/h2-5,12-14H,6-9H2,1H3 checkY
  • Key:YXDFSLSXLYAAPF-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester,4-fluorotropacocaine,3-Pseudotropyl-4-fluorobenzoate,3-pseudotropyl-4-fluorobenzoate,pFBT) is atropane derivative drug which acts as alocal anaesthetic, having around 30% the stimulant potency ofcocaine but around the same potency as a local anaesthetic.[citation needed] It has been investigated as a potentialradiolabelled agent for studyingreceptor binding,[1] but was not adopted for this application. The main application for fluorotropacocaine, however, has been as adesigner druganalogue of cocaine, first detected by theEMCDDA in 2008,[2][3] and subsequently sold as an ingredient of various "bath salt" powder products, usually mixed in combination with other stimulant drugs such ascaffeine,dimethocaine,desoxypipradrol orsubstituted cathinone derivatives.[4]

See also

[edit]

References

[edit]
  1. ^Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84.ISBN 0-306-44035-0
  2. ^Wohlfarth A, Weinmann W (May 2010). "Bioanalysis of new designer drugs".Bioanalysis.2 (5):965–79.doi:10.4155/bio.10.32.PMID 21083227.
  3. ^Kavanagh P, Angelov D, O'Brien J, Fox J, O'Donnell C, Christie R, et al. (January 2012). "The syntheses and characterization 3β-(4-fluorobenzoyloxy)tropane (fluorotropacocaine) and its 3α isomer".Drug Testing and Analysis.4 (1):33–8.doi:10.1002/dta.362.PMID 22102564.
  4. ^Reitzel LA, Dalsgaard PW, Müller IB, Cornett C (May 2012). "Identification of ten new designer drugs by GC-MS, UPLC-QTOF-MS, and NMR as part of a police investigation of a Danish internet company".Drug Testing and Analysis.4 (5):342–54.doi:10.1002/dta.358.PMID 22102551.
Adamantanes
Adenosine antagonists
Alkylamines
Ampakines
Arylcyclohexylamines
Benzazepines
Cathinones
Cholinergics
Convulsants
Eugeroics
Oxazolines
Phenethylamines
Phenylmorpholines
Piperazines
Piperidines
Phenethylpyrrolidines
Racetams
Psychedelics
Tropanes
Tryptamines
Others
Esters by acid
Aminobenzoic
Benzoic
ArCO2- (not para-amino or Ph)
Amides
Combinations
Retrieved from "https://en.wikipedia.org/w/index.php?title=3-(p-Fluorobenzoyloxy)tropane&oldid=1285148058"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp