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2C-T-8

From Wikipedia, the free encyclopedia
Pharmaceutical compound
2C-T-8
Clinical data
Other names4-Cyclopropylmethylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-cyclopropylmethylthiophenethylamine
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic;Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action10–15 hours[1]
Identifiers
  • 2-{4-[(cyclopropylmethyl)sulfanyl]-2,5-dimethoxyphenyl}ethan-1-amine
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC14H21NO2S
Molar mass267.39 g·mol−1
3D model (JSmol)
  • COc2cc(SCC1CC1)c(cc2CCN)OC
  • InChI=1S/C14H21NO2S/c1-16-12-8-14(18-9-10-3-4-10)13(17-2)7-11(12)5-6-15/h7-8,10H,3-6,9,15H2,1-2H3 checkY
  • Key:AHMSSHCYIDBVQB-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

2C-T-8, also known as4-cyclopropylmethylthio-2,5-dimethoxyphenethylamine, is apsychedelicphenethylamine of the2C family. It was first synthesized byAlexander Shulgin, sometimes used as anentheogen.

Use and effects

[edit]

In his bookPiHKAL, Shulgin lists the dosage range as 30 to 50 mg.[1] 2C-T-8 is generally taken orally and effects typically last 10 to 15 hours. Experiences have varied betweeninsight andcreativity at low doses tohypersensitivity andparanoia at higher doses. A "thinking-connection" that is characteristic of the2C-T group is evident in this chemical in stark contrast to the "pure euphoria" of phenethylamines such asMDMA.[1]

Toxicity

[edit]

The toxicity of 2C-T-8 is not well documented. 2C-T-8 is somewhat less potent than 2C-T-7, but it may be expected that at higher doses it would display similar toxicity to that of other phenethylamines of the 2C-T family.

There have been no confirmed deaths due to 2C-T-8,[citation needed] though this may in part be due to its rarity and limited usage. Of the 2C-T family, there have been a few confirmed deaths due to2C-T-7, which involved either insufflating large (>30 mg) doses[2][3] and in one case an unknown oral dose was combined with 200 mg MDMA.[4]

Interactions

[edit]
See also:Psychedelic drug § Interactions, andTrip killer § Serotonergic psychedelic antidotes

Chemistry

[edit]

The full name of the chemical is 2,5-dimethoxy-4-cyclopropylmethylthiophenethylamine. The compound is reported to have a bad taste and smell.[citation needed]

Society and culture

[edit]

Legal status

[edit]

2C-T-8 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-8 will probably be prosecuted under theFederal Analog Act because of its structural similarities to2C-T-7. However, 2C-T-8, unlike many otherphenethylamines has not been sold by internet retailers. In the wake ofOperation Web Tryp in July 2004, the issue of possession and sales of 2C-T-8 and other similar chemicals will probably be resolved in the courtroom as will the fate of this rare but uniquepsychedelic.[needs update]

Canada

[edit]

As of October 31, 2016, 2C-T-8 is a controlled substance (Schedule III) in Canada.[5]

See also

[edit]

References

[edit]
  1. ^abcdShulgin, Alexander;Shulgin, Ann (September 1991).PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.2C-T-8 Entry in PiHKAL
  2. ^Erowid.org
  3. ^Erowid.org
  4. ^Erowid.org
  5. ^"Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". 4 May 2016.

External links

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