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2C-T-21

From Wikipedia, the free encyclopedia
Psychedelic phenethylamine drug

2C-T-21
Names
Preferred IUPAC name
2-{4-[(2-Fluoroethyl)sulfanyl]-2,5-dimethoxyphenyl}ethan-1-amine
Other names
4-(2-Fluoroethylthio)-2,5-dimethoxyphenethylamine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C12H18FNO2S/c1-15-10-8-12(17-6-4-13)11(16-2)7-9(10)3-5-14/h7-8H,3-6,14H2,1-2H3 checkY
    Key: ZBUUUKBTOCTOPW-UHFFFAOYSA-N checkY
  • InChI=1/C12H18FNO2S/c1-15-10-8-12(17-6-4-13)11(16-2)7-9(10)3-5-14/h7-8H,3-6,14H2,1-2H3
    Key: ZBUUUKBTOCTOPW-UHFFFAOYAH
  • COc1cc(SCCF)c(cc1CCN)OC
Properties
C12H18FNO2S
Molar mass259.34 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

2C-T-21 (4-(2-fluoroethylthio)-2,5-dimethoxyphenethylamine) is apsychedelicphenethylamine of the2C family sometimes used as anentheogen. It was first synthesized byAlexander Shulgin.

Dosage

[edit]

In his bookPiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as 8–12 mg.[1]

Effects

[edit]

2C-T-21 is generally taken orally and effects typically last 7 to 10 hours.[1] The potential psychotherapeutic applications of this chemical were explored byMyron Stolaroff.[citation needed]

Pharmacology

[edit]

The mechanism that produces 2C-T-21's hallucinogenic and entheogenic effects has not been established; however, it may result from action as a5-HT2Aserotonin receptoragonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

Dangers

[edit]

On March 9, 2004, a 22-year-oldquadriplegic man named James Edwards Downs in St. Francisville, Louisiana, consumed an unknown dose of 2C-T-21 by sticking his tongue into a vial of powder he had purchased online. He developed a temperature of 108 °F (42 °C),[2] had atonic-clonic seizure, and slipped into a coma. Four days later, on March 13, Downs died at Lane Memorial Hospital in Zachary, LA.[citation needed]

This death became part of a two-year DEA investigation calledOperation Web Tryp which was launched in 2002. On July 22, 2004, the owners of American Chemical Supply were arrested on federal charges relating to distribution ofcontrolled substance analogues and the death of James Edwards Downs. Little is known about the toxicity of 2C-T-21 beyond this incident.

Legality

[edit]

2C-T-21 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-21 would probably be prosecuted under theFederal Analog Act because of its structural similarities to2C-T-7 and its known potential to cause death. In the wake ofOperation Web Tryp in July 2004, at least one distributor faced charges as a consequence of the death of James Downs from 2C-T-21 overdose.

Canada

[edit]

As of October 31, 2016, 2C-T-21 is a controlled substance (Schedule III) in Canada.[3]

References

[edit]
  1. ^abAlexander Shulgin. "2C-T-21".PiHKAL.
  2. ^"News from DEA, News Releases, 07/22/04". Archived fromthe original on February 8, 2008.
  3. ^Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)

External links

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