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2C-G

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(Redirected from2C-G-6)

Pharmaceutical compound
2C-G
Clinical data
Other names2C-G-0; 2,5-Dimethoxy-3,4-dimethylphenethylamine; 3,4-Dimethyl-2,5-dimethoxyphenethylamine; 3-Methyl-2C-D
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic;Hallucinogen
ATC code
  • None
Legal status
Legal status
  • In general Unscheduled
Pharmacokinetic data
Duration of action18–30 hours[1]
Identifiers
  • 2-(2,5-dimethoxy-3,4-dimethylphenyl)ethan-1-amine
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC12H19NO2
Molar mass209.289 g·mol−1
3D model (JSmol)
  • COc1c(C)c(C)c(cc1CCN)OC
  • InChI=1S/C12H19NO2/c1-8-9(2)12(15-4)10(5-6-13)7-11(8)14-3/h7H,5-6,13H2,1-4H3 checkY
  • Key:NFOHGLKGLZIHJQ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

2C-G, or2C-G-0, also known as3,4-dimethyl-2,5-dimethoxyphenethylamine or as3-methyl-2C-D, is apsychedelicphenethylamine of the2C family.[1] Firstsynthesized byAlexander Shulgin, it has structural and pharmacodynamic properties similar to2C-D andGanesha (G).[1] The drug has a number of knownhomologues, which are known as the 2C-G series of compounds.[1]

Use and effects

[edit]

InAlexander Shulgin's bookPiHKAL (Phenethylamines I Have Known and Loved), the dose range is listed as 20 to 35 mgorally.[1] Effects are similar to the relatedGanesha, and are extremely long lasting; theduration is 18 to 30 hours.[1]Visual effects are muted or absent, and it is described as an "insight-enhancer".[1] Unlike other members of the2C series, 2C-G is nearly as potent as itsamphetamine form.[1]

Interactions

[edit]
See also:Psychedelic drug § Interactions, andTrip killer § Serotonergic psychedelic antidotes

Chemistry

[edit]

Synthesis

[edit]

Thechemical synthesis of 2C-G has been described.[1]

Homologues

[edit]

Severalhomologues of 2C-G were also synthesized byAlexander Shulgin.[1] These include2C-G-3,2C-G-5, and2C-G-N.[1] Some, such as 2C-G-1, 2C-G-2,2C-G-4, and 2C-G-6, are possible to synthesize in principle but impossible or extraordinarily difficult to do so in practice.[1]

CompoundDetailsStructure
2C-G-1CAS: 2888537-47-9

The synthesis of this compound has not been reported, but it is described prophetically in WO2022271982

2C-G-2CAS: 2888537-48-0

The synthesis of this compound has not been reported, but it is described prophetically in WO2022271982

2C-G-3CAS: 207740-19-0

Dose: 16–25 mg
Duration: 12–24 hours
Effects: Some visual effects. General euphoria with an underlying sense of paranoia.

2C-G-4CAS: 952006-59-6

Partially synthesized but not tested.

2C-G-5CAS: 207740-20-3

Dose: 10–16 mg
Duration: 32–48 hours
Effects: Similar to2C-B for some users. General euphoria (sometimes followed by irritability), often leading to tiredness (likely due to duration).

2C-G-6CAS: 2888537-49-1

The synthesis of this compound has not been reported, but it is described prophetically in WO2022271982

2C-G-NCAS: 207740-21-4

Dose: 20–40 mg
Duration: 20–30 hours
Effects: Stimulation similar to that caused by amphetamines. General sense of unease or unfriendliness for most. 2C-G-N is sometimes called 2C-NPH due to thenaphthalene portion of the molecule.

History

[edit]

2C-G was first described in the literature byAlexander Shulgin in his 1991 bookPiHKAL (Phenethylamines I Have Known and Loved).[1]

Society and culture

[edit]

Legal status

[edit]

Canada

[edit]

As of October 31, 2016; 2C-G is a controlled substance (Schedule III) in Canada.[2]

United Kingdom

[edit]

2C-G and all other compounds featuring inPiHKAL areClass A drugs in theUnited Kingdom.

United States

[edit]

In the United States 2C-G is considered a Schedule Icontrolled substance as apositional isomer of2C-E andDOM.[3]

See also

[edit]

References

[edit]
  1. ^abcdefghijklmnShulgin AT, Shulgin A (1991)."2C-G".PiHKAL: A Chemical Love Story (1st ed.). Berkeley, CA: Transform Press.ISBN 978-0-9630096-0-9.OL 22859055M.
  2. ^"Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". 4 May 2016.
  3. ^"Lists of: Scheduling Actions - Controlled Substances - Regulated Chemicals"(PDF). Drug Enforcement Administration. February 2023.

External links

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