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2-Tetrahydrofurylethylamine

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Pharmaceutical compound
2-Tetrahydrofurylethylamine
Clinical data
Other namesTH-FEA; 2-(2-Tetrahydrofuryl)ethylamine; 2-Aminoethyltetrahydrofuran; Tetrahydrofurfurylmethylamine
Identifiers
  • 2-(oxolan-2-yl)ethanamine
CAS Number
PubChemCID
ChemSpider
CompTox Dashboard(EPA)
ECHA InfoCard100.252.264Edit this at Wikidata
Chemical and physical data
FormulaC6H13NO
Molar mass115.176 g·mol−1
3D model (JSmol)
  • C1CC(OC1)CCN
  • InChI=1S/C6H13NO/c7-4-3-6-2-1-5-8-6/h6H,1-5,7H2
  • Key:ZCOIVJPCZLPQPT-UHFFFAOYSA-N

2-Tetrahydrofurylethylamine (TH-FEA or2-(2-tetrahydrofuryl)ethylamine) is adrug related to thearylalkylamines.[1]Analogues include2-furylethylamine (FEA),2-pyrrolylethylamine (NEA),β-phenethylamine,amphetamine, andthiopropamine, among others.[1] A fewderivatives of TH-FEA are known.[1] The compound ispharmacologically active, producing a strong constricting effect on theuterus.[1][2] TH-FEA was first described in thescientific literature by 1920.[1]

References

[edit]
  1. ^abcdeShulgin A, Manning T, Daley PF (2011)."#67. FEA".The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley, CA: Transform Press. pp. 138–141.ISBN 978-0-9630096-3-0.OCLC 709667010.
  2. ^Windaus A, Dalmer O (1920). "Furethylamine and tetrahydrofurethylamine".Berichte Deutsch. Chem. Ges.53B:2304–2308.doi:10.1002/cber.19200531118.


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