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2-Pyrrolylethylamine

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Pharmaceutical compound
2-Pyrrolylethylamine
Clinical data
Other names2-(2-Pyrrolyl)ethylamine; NEA; 2-NEA
Identifiers
  • 2-(1H-pyrrol-2-yl)ethanamine
CAS Number
PubChemCID
ChemSpider
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC6H10N2
Molar mass110.160 g·mol−1
3D model (JSmol)
  • C1=CNC(=C1)CCN
  • InChI=1S/C6H10N2/c7-4-3-6-2-1-5-8-6/h1-2,5,8H,3-4,7H2
  • Key:IAZZNTYMXXEHHT-UHFFFAOYSA-N

2-Pyrrolylethylamine (NEA,2-NEA, or2-(2-pyrrolyl)ethylamine) is achemical compound of thearylalkylamine family.[1]

It is related to other arylalkylamines as well astrace amines includingtryptamine (2-indolylethylamine),phenethylamine (2-phenylethylamine),2-furylethylamine,thiopropamine (1-(2-thienyl)-2-aminopropane), andisocyclamine (cyclopentanylaminopropane), among others.[1] Many of these compounds aremonoamine releasing agents and/orreuptake inhibitors.[1]

NEA is known to bepharmacologically active itself, for instance havinghistamine-like activity on the isolatedguinea pigileum and having effects ongastric acidsecretion in dogs.[1]

The compound was first described in thescientific literature by 1949.[1]

See also

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References

[edit]
  1. ^abcdeShulgin A, Manning T, Daley PF (2011)."#67. FEA".The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley, CA: Transform Press. pp. 138–141.ISBN 978-0-9630096-3-0.OCLC 709667010.


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