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| Names | |
|---|---|
| Preferred IUPAC name 2-Phenyl-1-benzothiophene | |
Other names
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| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
| ChemSpider | |
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| Properties | |
| C14H10S | |
| Molar mass | 210.29 g·mol−1 |
| Melting point | 171.5 °C (340.7 °F; 444.6 K)[1] |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
2-Phenyl-1-benzothiophene is anaromatic chemical compound commonly used as an intermediate in the production ofmedication. Derivatives of the compound are present in drugs used to treatAlzheimer's disease, and its structure is present in theselective estrogen receptor modulator drugsraloxifene andarzoxifene.[2] Its formula isC14H10S.
2-Phenyl-1-benzothiophene is an intermediate inpesticide synthesis, in addition to its uses in thepharmaceutical field. Typically, it is produced through three methods: anarylation reaction ofbenzothiophene; acoupling reaction between2-benzothiophene boronic acid and abenzene-donating compound; orcyclization of aromatic molecules.[3]
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