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| Names | |
|---|---|
| IUPAC name 2-O-[(9Z)-Octadec-9-enoyl]glycerol | |
| Systematic IUPAC name 1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate | |
| Other names 2-Monoolein | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider |
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| UNII | |
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| Properties | |
| C21H40O4 | |
| Molar mass | 356.547 g·mol−1 |
| Density | 0.958 g/cm3 |
| Hazards | |
| Flash point | > 113.0 °C (235.4 °F; 386.1 K) |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
2-Oleoylglycerol (2OG) is amonoacylglycerol that is found in biologic tissues. Its synthesis is derived fromdiacylglycerol precursors. It is metabolized tooleic acid andglycerol primarily by the enzymemonoacylglycerol lipase (MAGL).[1] In 2011, 2OG was found to be an endogenous ligand toGPR119.[2] 2OG has been shown to increaseglucagon-like peptide-1 (GLP-1) andgastric inhibitory polypeptide (GIP) levels following administration to thesmall intestine.[2] 2OG has also been discovered to potentiate G protein and not β-arrestin signaling via allosteric binding of the 5-HT2A receptor.[3]
