Ohio elected its members October 13, 1818.
| District | Incumbent | This race | |||
|---|---|---|---|---|---|
| Member | Party | First elected | Results | Candidates[a] | |
| Ohio 1 | William Henry Harrison | Democratic-Republican | 1816 | Incumbent retired. New member elected. Democratic-Republican hold. | √Thomas R. Ross (Democratic-Republican) 48.7% John H. Platt 28.9% Ethan Stone 22.4% |
| Ohio 2 | John W. Campbell | Democratic-Republican | 1816 | Incumbent re-elected. | √John W. Campbell (Democratic-Republican) 93.0% James Burin 7.0% |
| Ohio 3 | Levi Barber | Democratic-Republican | 1816 | Incumbent lost re-election. New member elected. Democratic-Republican hold. | √Henry Brush (Democratic-Republican) 41.1% Levi Barber (Democratic-Republican) 30.3% Edward Tupper 28.6% |
| Ohio 4 | Samuel Herrick | Democratic-Republican | 1816 | Incumbent re-elected. | √Samuel Herrick (Democratic-Republican) 52.9% John C. Wright (Federalist) 46.4% |
| Ohio 5 | Philemon Beecher | Federalist | 1816 | Incumbent re-elected. | √Philemon Beecher (Federalist) 51.6% Joseph Vance (Democratic-Republican) 47.7% |
| Ohio 6 | Peter Hitchcock | Democratic-Republican | 1816 | Incumbent lost re-election. New member elected. Democratic-Republican hold. | √John Sloane (Democratic-Republican) 51.7% Peter Hitchcock (Democratic-Republican) 46.2% Benjamin Martin 2.1% |
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