 | |
| Names | |
|---|---|
| IUPAC name 3,16β-Dihydroxyestra-1,3,5(10)-trien-17-one | |
| Systematic IUPAC name (2S,3aS,3bR,9bS,11aS)-2,7-Dihydroxy-11a-methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1H-cyclopenta[a]phenanthren-1-one | |
| Other names 16β-OH-E1 | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
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| Properties | |
| C18H22O3 | |
| Molar mass | 286.371 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
16β-Hydroxyestrone (16β-OH-E1) is anendogenousestrogen which serves as ametabolite ofestrone as well as ametabolic intermediate in thetransformation of estrone intoepiestriol (16β-hydroxyestradiol).[1][2] 16β-Hydroxyestrone has similarestrogenic activity to that of16α-hydroxyestrone.[2] It is lesspotent thanestradiol orestrone but can produce similar maximaluterotrophy at sufficiently high doses, suggesting a fullyestrogenic profile.[2]
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