| Names | |
|---|---|
| IUPAC name 17β-Hydroxyandrost-4-ene-3,11-dione | |
| Systematic IUPAC name (1S,3aS,3bS,9aR,9bS,11aS)-1-Hydroxy-9a,11a-dimethyl-2,3,3a,3b,4,5,8,9,9a,9b,11,11a-dodecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione | |
| Other names 11-Ketotestosterone; 11-Oxotestosterone | |
| Identifiers | |
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3D model (JSmol) | |
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| UNII | |
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| Properties | |
| C19H26O3 | |
| Molar mass | 302.40794 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
11-Ketotestosterone (11-KT) is an oxidized form oftestosterone that contains aketo group at the C11 position. It is related toadrenosterone, an androgen found in trace quantities in humans. Infish, 11-ketotestosterone functions as the endogenousandrogenic sex hormone.[1][2] Inmidshipman fish, 11-ketotestosterone is not present in females or Type II Males — Type II Males reach sexual maturation later, are less territorial, and have higher testosterone than Type I Males.
In mammals, 11-ketotestosterone has similar potency to testosterone as anandrogen, and has been identified as an importantadrenal androgen.[3] However, unlike testosterone, it is very weakly anabolic and mostly prevents muscle breakdown as opposed to promoting muscle growth. It is synthesized from11β-hydroxyandrostenedione and, to a lesser extent,11-ketoandrostenedione (adrenosterone).[3] 11-Ketoandrostenedione has notably been sold online as anandrogen prohormone, usually under the name 11-oxoandrostenedione (11-OXO).[3]