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| Formula | C16H24N2O2 |
| Molar mass | 276.380 g·mol−1 |
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1-Boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) is a compound used as an intermediate in the manufacture offentanyl, as well as various related derivatives such asbutyrylfentanyl,furanylfentanyl,benzylfentanyl andhomofentanyl, among others. It is an N-protected derivative of4-anilinopiperidine which can be readily converted to fentanyl or relatedanalogues in several straightforward synthetic steps. It was classified as aDEAList 1 Chemical in 2022, and is also controlled in various other jurisdictions. Its possession, sale and importation are consequently heavily regulated throughout much of the world.[1] 1-Boc-4-AP has also been identified as an impurity in otherdesigner drug products, though it is unclear if it has any pharmacological activity in its own right.[2]
