| [isocitrate dehydrogenase (NADP+)] kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.11.5 | ||||||||
| CAS no. | 83682-93-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDBPDBePDBsum | ||||||||
| Gene Ontology | AmiGO /QuickGO | ||||||||
| |||||||||
Inenzymology, a[isocitrate dehydrogenase (NADP+)] kinase (EC2.7.11.5) is anenzyme thatcatalyzes thechemical reaction:
Thus, the twosubstrates of this enzyme areATP andisocitrate dehydrogenase (NADP+), whereas its twoproducts areADP andisocitrate dehydrogenase (NADP+) phosphate.
This enzyme belongs to the family oftransferases, specifically those transferring a phosphate group to the sidechainoxygen atom ofserine orthreonine residues inproteins (protein-serine/threonine kinases).
Thesystematic name of this enzyme class isATP:[isocitrate dehydrogenase (NADP+)] phosphotransferase. Other names in common use include[isocitrate dehydrogenase (NADP+)] kinase,ICDH kinase/phosphatase,IDH kinase,IDH kinase/phosphatase,IDH-K/P,IDHK/P,isocitrate dehydrogenase kinase (phosphorylating),isocitrate dehydrogenase kinase/phosphatase, andSTK3.
