 | |
| Names | |
|---|---|
| IUPAC name H-Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp-OH | |
| Other names beta-MSH, β-melanotropin, β-melanocortin, β-intermedin | |
| Identifiers | |
3D model (JSmol) | |
| Abbreviations | AEKKDEGPYRMEHFRWGSPPKD |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| KEGG | |
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| Properties | |
| C118H174N34O35S | |
| Molar mass | 2660.95 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
β-Melanocyte-stimulating hormone (β-MSH) is anendogenouspeptide hormone andneuropeptide.[1] It is amelanocortin, specifically, one of the three types ofmelanocyte-stimulating hormone (MSH), and is produced fromproopiomelanocortin (POMC).[1] It is anagonist of theMC1,MC3,MC4, andMC5 receptors.[1] It contains 23 amino acid residues.
β-MSH is also known to decrease food intake in animals such as rats, chicken due to the effect ofproopiomelanocortin (POMC).[2] Research was performed to see the effect β-MSH has on chicks, and it has been found that chicks responded with a decrease in food and water intake when treated with β-MSH. The experiment showed that β-MSH causes anorexigenic effects in chicks.[3]
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