Pythodoros of Tralles, also known asPythodorus (Ancient Greek:Πυθόδωρος; c. 70 – after 28 BC), was an exceedingly wealthyGreek living in the 1st century BC. Pythodoros originally came from Tralles (modernAydın,Turkey). Not much is known about his family. He was a friend to the Roman triumvirPompey.^{[1][2][3][4][5]}

Pythodoros became the first son-in-law of theRoman triumvirMark Antony. In 36 BC, Pythodoros had married to one of Antony’s eldest children, his daughterAntonia.^[6] Antonia was the daughter and only child from the triumvir’s second marriage to his paternal cousin Antonia Hybrida Minor. His wife was about 20 years younger than he was. The reason that Antony arranged for Pythodoros to marry his daughter was to hopefully gain some of Pythodoros’ wealth for his war chest in his campaign to invadeParthia. However, it is uncertain if Antony ever managed to do this.

Pythodoros and his wife settled in Smyrna (modernİzmir,Turkey). Either in 30 BC or 29 BC, Antonia bore Pythodoros a daughter and only childPythodorida, who through her marriages became Queen ofPontus andCappadocia. Pythodorida was born and raised in Smyrna.