Amyelocyte is a youngcell of thegranulocytic series, occurring normally inbone marrow (can be found in circulatingblood when caused by certain diseases).
| Myelocyte | |
|---|---|
 | |
| Details | |
| Precursor | Promyelocyte |
| Gives rise to | Metamyelocyte |
| Location | Bone marrow |
| Identifiers | |
| TH | H2.00.04.3.04004 |
| FMA | 83525 |
| Anatomical terms of microanatomy | |
Structure
editWhen stained with the usual dyes, thecytoplasm is distinctlybasophilic and relatively more abundant than inmyeloblasts orpromyelocytes, even though myelocytes are smaller cells.
Numerous cytoplasmicgranules are present in the more mature forms of myelocytes. Neutrophilic and eosinophilic granules areperoxidase-positive, while basophilic granules are not.
The nuclearchromatin is coarser than that observed in a promyelocyte, but it is relatively faintly stained and lacks a well-defined membrane.
The nucleus is fairly regular in contour (not indented), and seems to be 'buried' beneath the numerous cytoplasmic granules. (If the nucleus were indented, it would likely be ametamyelocyte.)
Measurement
editThere is an internationally agreed method of counting blasts, with results from M1 upwards.
Development
editPromyelocyte → Myelocytes →metamyelocytes.
Additional images
edit_diagram_en.svg)
See also
editReferences
edit- ^Histology image:01809loa fromVaughan, Deborah (2002).A Learning System in Histology: CD-ROM and Guide.Oxford University Press.ISBN 978-0195151732.
- ^Histology image:01810loa fromVaughan, Deborah (2002).A Learning System in Histology: CD-ROM and Guide.Oxford University Press.ISBN 978-0195151732.
- ^Histology image:01804loa fromVaughan, Deborah (2002).A Learning System in Histology: CD-ROM and Guide.Oxford University Press.ISBN 978-0195151732.
External links
edit- Neutrophilic Myelocyte Presented by the University of Virginia
- Eosinophilic Myelocyte Presented by the University of Virginia
- Basophilic Myelocyte Presented by the University of Virginia
- Image at queensu.caArchived 2007-08-27 at theWayback Machine