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Integrin alpha D

From Wikipedia, the free encyclopedia
(Redirected fromITGAD)
Protein-coding gene in the species Homo sapiens

ITGAD
Identifiers
AliasesITGAD, ADB2, CD11D, integrin subunit alpha D
External IDsOMIM:602453;MGI:3578624;HomoloGene:56919;GeneCards:ITGAD;OMA:ITGAD - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for ITGAD
Genomic location for ITGAD
Band16p11.2Start31,393,335bp[1]
End31,426,505bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for ITGAD
Genomic location for ITGAD
Band7|7 F3Start127,753,548bp[2]
End127,822,988bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • spleen

  • gastrocnemius muscle

  • lymph node

  • muscle of thigh

  • appendix

  • blood

  • decidua

  • right lobe of liver

  • gallbladder
Top expressed in
  • spleen

  • spermatid

  • testicle

  • spermatocyte

  • islet of Langerhans

  • bone marrow

  • embryo

  • granulocyte

  • thymus

  • primary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

3681

381924

Ensembl

ENSG00000156886

ENSMUSG00000070369

UniProt

Q13349

Q3V0T4

RefSeq (mRNA)

NM_005353
NM_001318185

NM_001029872
NM_001177632

RefSeq (protein)

NP_001305114
NP_005344

NP_001025043

Location (UCSC)Chr 16: 31.39 – 31.43 MbChr 7: 127.75 – 127.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Integrin alpha-D is aprotein that inhumans isencoded by theITGADgene.[5][6][7]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000156886 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000070369 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Wong DA, Davis EM, LeBeau M, Springer TA (Aug 1996). "Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit".Gene.171 (2):291–4.doi:10.1016/0378-1119(95)00869-1.PMID 8666289.
  6. ^Shelley CS, Da Silva N, Georgakis A, Chomienne C, Arnaout MA (Aug 1998). "Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb".Genomics.49 (2):334–6.doi:10.1006/geno.1998.5232.PMID 9598326.
  7. ^"Entrez Gene: ITGAD integrin, alpha D".

Further reading

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External links

[edit]
Alpha
Beta
Dimers
Cytoadhesin receptor:
Fibrinogen receptor:
Fibronectin receptor:
Leukocyte-adhesion receptor:
Very late antigen receptor:
Vitronectin receptor:
1–50
51–100
101–150
151–200
201–250
251–300
301–350


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