Hypertrophy

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Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its componentcells.^[1] It is distinguished fromhyperplasia, in which the cells remain approximately the same size but increase in number.^[2] Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of thehormonally induced proliferation and enlargement of the cells of theuterus duringpregnancy.

Hypertrophy

Hypertrophy results from an increase in cell size, whereashyperplasia stems from an increase in cell number.

Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to theleft ventricle of heart.^[3]Sarcomeres are added in series, as for example indilated cardiomyopathy (in contrast tohypertrophic cardiomyopathy, a type ofconcentric hypertrophy, where sarcomeres are added in parallel).