d-DOPA(D-3,4-dihydroxyphenylalanine;dextrodopa) is similar toL-DOPA (levodopa), but with oppositechirality.Levo- anddextro- rotation refer to a molecule's ability to rotate planes ofpolarized light in one or the other direction. WhereasL-DOPA is moderately effective in thetreatment ofParkinson's disease (PD) anddopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain,D-DOPA isbiologically inactive.
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Names | |
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IUPAC name 3,4-Dihydroxy-D-phenylalanine | |
Systematic IUPAC name (2R)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
ECHA InfoCard | 100.024.858![]() |
UNII | |
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Properties | |
C9H11NO4 | |
Molar mass | 197.19 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). |
See also
edit- l-DOPA (Levodopa; Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc.)
- l-DOPS (Droxidopa)
- Methyldopa (Aldomet, Apo-Methyldopa, Dopamet, Novomedopa, etc.)
- Dopamine (Intropan, Inovan, Revivan, Rivimine, Dopastat, Dynatra, etc.)
- Norepinephrine (Noradrenaline; Levophed, etc.)
- Epinephrine (Adrenaline; Adrenalin, EpiPen, Twinject, etc.)
References
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