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  1. ECHA
  2. Search for chemicals
  3. Biocidal Active Substances

Information on biocides

Nested Applications

Information on biocides

Biocidal Active Substances

The basic principle in the Biocidal Products Regulation ((EU) No 528/2012 (BPR)) is that a biocidal product must be authorised before it can be made available on the market or used in the European Economic Area (EEA) and Switzerland. This takes place in two consecutive steps. First, the active substance is evaluated and, provided the criteria are fulfilled, is then approved in a specified product-type. The second step is the authorisation of each product consisting of, containing or generating the approved active substance(s). This page concerns the first step.

The data onthis page is active substance/product-type centric. This is reflected in all the search filters and results of the searches. Subsequently the table below displays information per active substance/product-type combination. For efficiency reasons, the term active substance is used interchangeable with the term active substance/product-type combination.

The database includes active substances in the Review Programme, active substances not in the Review Programme as well as substances in Annex I of the BPR. More information on the categorisation of active substances can be read inApproval of active substances page.

For further information on searches you can perform and how the information is presented please read on.

How to search

You can view the information on biocidal active substances in two ways:

- per specific active substance and product-type combination (use the Search tab); and

- as a summary of all product-type applications that have been submitted for a given active substance (Summary tab).

Using the Search tab, you can search with:

- Active substance details: substance identifiers, product-type, candidate for substitution.
(The default status for the field Candidate for substitution is “under assessment” and this status does not necessarily imply that the active substance is suspected Candidate for substitution. Provided the active substance is identified or not as a potential candidate for substitution, the status on the dissemination page changes accordingly to “yes” or “no”.)

- Approval data: for example the status of an application for approval, the assessment step in the approval process, validity of the approval granted.

- Related authorised biocidal products (trade name of a biocidal product).

How the information is presented

The results table presents information on an active substance, such as approval start and end date, evaluating competent authority and approval or assessment status. The substance name is a link to the substance information page (Infocard) which summarises information on a substance from all regulatory contexts managed by ECHA.

The data on active substances is collected from the Register for Biocidal Products (R4BP 3). It covers information on active substances for which an application for approval for a specific biocidal product-type has been submitted under the BPR or Biocidal Products Directive (Directive 98/8/EC). Please note that the validation step in R4BP 3 must be successfully passed for active substances to be disseminated or for the most recent status in the application process to be displayed.

More information on a specific active substance approval can be found in the factsheet (accessible through the eye icon in the results table). The factsheet holds details on the latest approval data, including relevant documents, related authorised biocidal products, and an overview of all the changes on the active substance approval.

In the results table, the number of related authorised biocidal products is also visible. The number represents the count of product clusters (groups of authorisations) containing the given active substance.

The Summary tab lists all product-type applications that have been submitted for a given active substance, regardless approval has been granted or refused. The approval status of an active substance and product-type combination is described with an icon. Hovering your mouse over the icon, you can see the status of an application for approval, the assessment step if the approval process is ongoing, and you can access the active substance factsheet.

Export results

You can export the active substance results to the ECHA website standard formats (XLS, CSV and XML).

Active Substances

Last updated 11 February 2026. Database contains 949 active substance-product type and Annex I records for which approval has been sought.
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Active substance
Active Substances
Active substance identifiers
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Approval data
Active Substances
Administrative identifiers
Validity of approval
Start date
End date
Approval identifiers
Related authorised biocidal products
Active Substances
SearchClear All
No results were found.
 
Annex I Substance(+)-Tartaric acid201-766-087-69-401/09/2013-
ApprovedLink to the factsheet15
(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl (1R-trans)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclo-propanecarboxylate (d-Tetramethrin)214-619-01166-46-7PT18 iconPT18Germany
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(13Z)-Hexadec-13-en-11-yn-1-yl acetate642-968-278617-58-0PT19 iconPT1901/06/202331/05/2033France
ApprovedLink to the factsheet1
(2R,6aS,12aS)-1,2,6,6a,12,12a-hexa- hydro-2-isopropenyl-8,9-dimethoxychro- meno[3,4-b]furo[2,3-h]chromen-6-one (Rotenone)201-501-983-79-4PT17 iconPT17Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(9Z,12E)-Tetradeca-9, 12-dien-1-yl acetate608-490-330507-70-1PT19 iconPT19Austria
No longer supportedLink to the factsheet12
Annex I Substance(9Z,12E)-tetradeca-9,12-dien-1-yl acetate608-490-330507-70-101/09/2013-
ApprovedLink to the factsheet24
(benzothiazol-2-ylthio)methyl thiocyanate (TCMTB)244-445-021564-17-0PT09 iconPT09Norway
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(benzothiazol-2-ylthio)methyl thiocyanate (TCMTB)244-445-021564-17-0PT12 iconPT12Norway
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3- methyl-2-nitroguanidine (Clothianidin)433-460-1210880-92-5PT08 iconPT0801/02/201031/01/2020Germany
ExpiredLink to the factsheet
(E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3- methyl-2-nitroguanidine (Clothianidin)433-460-1210880-92-5PT18 iconPT1801/10/201630/09/2026Germany
ApprovedLink to the factsheet5
(ethylenedioxy)dimethanol (Reaction products of ethylene glycol with paraformaldehyde (EGForm))222-720-63586-55-8PT02 iconPT02Poland
No longer supportedLink to the factsheet
(ethylenedioxy)dimethanol (Reaction products of ethylene glycol with paraformaldehyde (EGForm))222-720-63586-55-8PT06 iconPT06Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(ethylenedioxy)dimethanol (Reaction products of ethylene glycol with paraformaldehyde (EGForm))222-720-63586-55-8PT11 iconPT11Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(ethylenedioxy)dimethanol (Reaction products of ethylene glycol with paraformaldehyde (EGForm))222-720-63586-55-8PT12 iconPT12Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(ethylenedioxy)dimethanol (Reaction products of ethylene glycol with paraformaldehyde (EGForm))222-720-63586-55-8PT13 iconPT13Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
(RS)-3-Allyl-2-methyl-4-oxocyclopent-2- enyl (1R,3R)-2,2-dimethyl-3-(2-methyl- prop-1-enyl)-cyclopropanecarboxylate (mixture of 2 isomers 1R trans: 1R/S only 1:3) (Esbiothrin)807-421-6260359-57-7PT18 iconPT18Germany
Not approvedLink to the factsheet
(RS)-3-Allyl-2-methyl-4-oxocyclopent-2- enyl-(1R,3R;
1R,3S)-2,2-dimethyl-3-(2- methylprop-1-enyl)-cyclopropanecarboxy- late (mixture of 4 isomers 1R trans, 1R:1R trans, 1S: 1R cis, 1R: 1R cis,1S 4:4:1:1) (d-Allethrin)
687-634-7231937-89-6PT18 iconPT18Germany
Not approvedLink to the factsheet
(RS)-α-cyano-3phenoxybenzyl-(1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate (Cypermethrin)257-842-952315-07-8PT08 iconPT0801/06/201530/11/2027Belgium
ApprovedLink to the factsheet81
(RS)-α-cyano-3phenoxybenzyl-(1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate (Cypermethrin)257-842-952315-07-8PT18 iconPT1801/06/202031/05/2030Belgium
ApprovedLink to the factsheet156
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT02 iconPT02Spain
No longer supportedLink to the factsheet
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT06 iconPT0601/10/202630/09/2036Spain
ApprovedLink to the factsheet
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT09 iconPT09Spain
Commission decision (participant withdrawal)
-
Link to the factsheet
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT10 iconPT10Spain
No longer supportedLink to the factsheet
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT11 iconPT11Spain
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT12 iconPT12Spain
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
1,2-benzisothiazol-3(2H)-one (BIT)220-120-92634-33-5PT13 iconPT1301/10/202630/09/2036Spain
ApprovedLink to the factsheet
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (DMDMH)229-222-86440-58-0PT06 iconPT06Poland
Initial application for approval in progress
Opinion development by BPC
Link to the factsheet
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (DMDMH)229-222-86440-58-0PT13 iconPT13Poland
Initial application for approval in progress
Opinion development by BPC
Link to the factsheet
1-(3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl)-3-(2,6-difluorobenzoyl) urea (Hexaflumuron)401-400-186479-06-3PT18 iconPT1801/04/201731/03/2027Greece
Approved - Renewal in progress
Competent authority evaluation
Link to the factsheet
1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole (Imazalil)252-615-035554-44-0PT03 iconPT03Germany
No longer supportedLink to the factsheet
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole (Propiconazole)262-104-460207-90-1PT07 iconPT0701/12/201630/11/2026Finland
ApprovedLink to the factsheet1
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole (Propiconazole)262-104-460207-90-1PT08 iconPT0801/04/201030/11/2030Finland
ApprovedLink to the factsheet978
1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole (Propiconazole)262-104-460207-90-1PT09 iconPT09Finland
Link to the factsheet
1-ethynyl-2-methylpent-2-enyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate (Empenthrin)259-154-454406-48-3PT18 iconPT18Belgium
Not approvedLink to the factsheet
1R-trans phenothrin247-431-226046-85-5PT18 iconPT1801/09/201529/02/2028Ireland
Approved - Renewal in progress
Competent authority evaluation
Link to the factsheet37
2,2-dibromo-2-cyanoacetamide (DBNPA)233-539-710222-01-2PT02 iconPT02Denmark
No longer supportedLink to the factsheet
2,2-dibromo-2-cyanoacetamide (DBNPA)233-539-710222-01-2PT04 iconPT04Denmark
Not approvedLink to the factsheet
2,2-dibromo-2-cyanoacetamide (DBNPA)233-539-710222-01-2PT06 iconPT0601/11/202631/10/2031Denmark
ApprovedLink to the factsheet
2,2-dibromo-2-cyanoacetamide (DBNPA)233-539-710222-01-2PT11 iconPT11Denmark
Initial application for approval in progress
Commission decision
Link to the factsheet
2,2-dibromo-2-cyanoacetamide (DBNPA)233-539-710222-01-2PT12 iconPT12Denmark
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
2,2-dibromo-2-cyanoacetamide (DBNPA)233-539-710222-01-2PT13 iconPT13Denmark
No longer supportedLink to the factsheet
2,2′,2′′-(hexahydro-1,3,5-triazine-1,3,5- triyl)triethanol (HHT)225-208-04719-04-4PT06 iconPT06Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
2,2′,2′′-(hexahydro-1,3,5-triazine-1,3,5- triyl)triethanol (HHT)225-208-04719-04-4PT11 iconPT11Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
2,2′,2′′-(hexahydro-1,3,5-triazine-1,3,5- triyl)triethanol (HHT)225-208-04719-04-4PT12 iconPT12Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
2,2′,2′′-(hexahydro-1,3,5-triazine-1,3,5- triyl)triethanol (HHT)225-208-04719-04-4PT13 iconPT13Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
2,2′-dithiobis[N-methylbenzamide] (DTBMA)219-768-52527-58-4PT06 iconPT06Poland
Initial application for approval in progress
Competent authority evaluation
Link to the factsheet
2-(2-butoxyethoxy)ethyl 6-propylpiper-onyl ether (Piperonyl butoxide/PBO)200-076-751-03-6PT18 iconPT1801/07/201830/06/2028Greece
ApprovedLink to the factsheet38
2-bromo-2-(bromomethyl)pentanedinitrile (DBDCB)252-681-035691-65-7PT06 iconPT0601/01/201831/12/2027Czechia
ApprovedLink to the factsheet
2-Butanone, peroxide215-661-21338-23-4PT01 iconPT01Hungary
Not approvedLink to the factsheet
2-Butanone, peroxide215-661-21338-23-4PT02 iconPT02Hungary
Not approvedLink to the factsheet

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