- Article
- Published:
Central Dogma of Molecular Biology
Naturevolume 227, pages561–563 (1970)Cite this article
49kAccesses
131Altmetric
Abstract
The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred from protein to either protein or nucleic acid.
This is a preview of subscription content,access via your institution
Access options
Subscription info for Japanese customers
We have a dedicated website for our Japanese customers. Please go tonatureasia.com to subscribe to this journal.
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Deciphering protein post-translational modifications using chemical biology tools
The structural basis of the genetic code: amino acid recognition by aminoacyl-tRNA synthetases
References
Nature,226, 1198 (1970).
Temin, H. M., and Mizutani, S.,Nature,226, 1211 (1970). This article contains the references to Dr Temin's earlier work dating back to 1963.
Baltimore, D.,Nature,226, 1209 (1970). See also the brief account of Spiegelman's recent work on page 1202.
Crick, F. H. C., inSymp. Soc. Exp. Biol., The Biological Replication of Macromolecules, XII, 138 (1958).
Commoner, B.,Nature,220, 334 (1968).
Fleischman, P.,Nature,225, 30 (1970).
Hershey, A. D.,Nature,226, 697 (1970).
McCarthy, B., and Holland, J. J.,Proc. US Nat. Acad. Sci.,54, 880 (1965).
Gibbons, R. A., and Hunter, G. D.,Nature,215, 1041 (1967).
Griffith, J. S.,Nature,215, 1043 (1967).
Author information
Authors and Affiliations
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH
FRANCIS CRICK
- FRANCIS CRICK
You can also search for this author inPubMed Google Scholar
Rights and permissions
About this article
Cite this article
CRICK, F. Central Dogma of Molecular Biology.Nature227, 561–563 (1970). https://doi.org/10.1038/227561a0
Received:
Issue Date:
This article is cited by
The hidden impact of in-source fragmentation in metabolic and chemical mass spectrometry data interpretation
- Martin Giera
- Aries Aisporna
- Gary Siuzdak
Nature Metabolism (2024)
Cell-type specific and differential expression of LINC-RSAS long noncoding RNA declines in the testes during ageing of the rat
- Ajay Kumar Danga
- Sukhleen Kour
- Pramod C. Rath
Biogerontology (2024)
Whole Blood Transcriptome Analysis in Patients with Trigeminal Neuralgia: a Prospective Clinical Study
- Tianyu Liu
- Chao Xu
- Yi Feng
Journal of Molecular Neuroscience (2024)
Liver cancer-specific mutations in functional domains of ADAR2 lead to the elevation of coding and non-coding RNA editing in multiple tumor-related genes
- Jian Li
- Chaowei Li
- Wengui Xu
Molecular Genetics and Genomics (2024)
GKLOMLI: a link prediction model for inferring miRNA–lncRNA interactions by using Gaussian kernel-based method on network profile and linear optimization algorithm
- Leon Wong
- Lei Wang
- Mei-Yuan Cao
BMC Bioinformatics (2023)
