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5 May 2004Usefulness of image morphing techniques in cancer treatment by conformal radiotherapy

Hussein Atoui, David Sarrut,Serge Miguet

Hussein Atoui,¹ David Sarrut,^2,3 Serge Miguet³

¹Institut National de la Sante et de la Recherche Medicale (France)
²Ctr. Leon Berard (France)
³Lab. LIRIS (France)

Proceedings Volume 5367, Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display; (2004)https://doi.org/10.1117/12.533009
Event:Medical Imaging 2004, 2004, San Diego, California, United States

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Abstract

Conformal radiotherapy is a cancer treatment technique, that targets high-energy X-rays to tumors with minimalexposure to surrounding healthy tissues. Irradiation ballistics is calculated based on an initial 3D ComputerizedTomography (CT) scan. At every treatment session, the random positioning of the patient, comparedto the reference position defined by the initial 3D CT scan, can generate treatment inaccuracies. Positioningerrors potentially predispose to dangerous exposure to healthy tissues as well as insufficient irradiation to thetumor. A proposed solution would be the use of portal images generated by Electronic Portal Imaging Devices(EPID). Portal images (PI) allow a comparison with reference images retained by physicians, namely DigitallyReconstructed Radiographs (DRRs). At present, physicians must estimate patient positional errors by visualinspection. However, this may be inaccurate and consumes time. The automation of this task has been thesubject of many researches. Unfortunately, the intensive use of DRRs and the high computing time requiredhave prevented real time implementation. We are currently investigating a new method for DRR generation thatcalculates intermediate DRRs by 2D deformation of previously computed DRRs. We approach this investigationwith the use of a morphing-based technique named mesh warping.

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Hussein Atoui,David Sarrut, andSerge Miguet"Usefulness of image morphing techniques in cancer treatment by conformal radiotherapy", Proc. SPIE 5367, Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display, (5 May 2004);https://doi.org/10.1117/12.533009

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