Visualization of age-dependent myocardial metabolic impairment in cardiomyopathic model hamster obtained by fluorescent X-ray computed tomography using I-127 BMIPP

Thet-Thet-Lwin,T. Takeda,J. Wu,Q. Huo,T. Yuasa,K. Hyodo andT. Akatsuka

Fluorescent X-ray computed tomography (FXCT) enables visualization of myocardial fatty acid metabolism by using non-radio-iodinated I-5-(p-iodophenyl)-3-(R,S)-methylpentadecanoice acid (BMIPP). In this experiment, age-dependent myocardial metabolic impairment was successfully imaged and analyzed quantitatively in J2N-k cardiomyopathic hamster using FXCT.

Keywords:fluorescent X-ray computed tomography;age-dependent metabolic impairment;cardiomyopathy;myocardial fatty acid;BMIPP.

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Visualization of age-dependent myocardial metabolic impairment in cardiomyopathic model hamster obtained by fluorescent X-ray computed tomography using I-127 BMIPP