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Infectious diseases: Edited by Alimuddin Zumla

Parasitic lung infections

Vijayan, Vannan Kandi

Author Information

Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

Correspondence to Dr Vannan Kandi Vijayan, MD, PhD, DSc, FAMS, Director, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110007, India Tel: +91 11 27667027; fax: +91 11 27667420; e-mail:[email protected]

Current Opinion in Pulmonary Medicine15(3):p 274-282, May 2009. |DOI:10.1097/MCP.0b013e328326f3f8

Abstract

Purpose of review 

Global climate change and population explosion leading to changes in natural ecosystem and travel across the continents have resulted in an increase in the transmission of parasites to human beings. This review focuses on recent advancements in parasitic lung infections.

Recent findings 

Invasive parasitic diseases including lung infections are increasingly being reported in patients with immunodeficiency syndromes. A recombinant kinesin-related antigen ofLeishmania donovani has been validated with ELISA using urine samples for the diagnosis of visceral leishmaniasis. Pyruvate kinase deficiency has been shown to provide protection againstPlasmodium falciparum infection. Intravenous artesunate is an alternative drug for the treatment of severe malaria. The best way to protect from malaria is the use of long-lasting insecticide-treated bednets. Biennial treatment with praziquantel has been found to be cost-effective treatment for control of infection withSchistosoma haematobium. Pulmonary paragonimiasis can be diagnosed by fine needle aspiration biopsy of pulmonary nodules.Strongyloides stercoralis hyperinfection can mimic accelerated idiopathic pulmonary fibrosis. Migratory nodular shadows with halos are important chest computed tomographic findings in human toxocariasis.

Summary 

Patients with immunodeficiency syndromes (HIV infection, organ transplantation and immunosuppressive drugs, including corticosteroids) should be evaluated for early detection of parasitic lung infections.

© 2009 Lippincott Williams & Wilkins, Inc.

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Current Opinion in Pulmonary Medicine15(3):274-282, May 2009.
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