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Original Articles

The Uniform Data Set (UDS): Clinical and Cognitive Variables and Descriptive Data From Alzheimer Disease Centers

Morris, John C. MD*; Weintraub, Sandra PhD; Chui, Helena C. MD; Cummings, Jeffrey MD§; DeCarli, Charles MD; Ferris, Steven PhD; Foster, Norman L. MD#; Galasko, Douglas MD**; Graff-Radford, Neill MD††; Peskind, Elaine R. MD‡‡; Beekly, Duane BS§§; Ramos, Erin M. MPH§§; Kukull, Walter A. PhD§§

Author Information

*Washington University, St Louis, MO

Northwestern University, Chicago, IL

University of Southern California

§University of California, Los Angeles, CA

University of California, Davis, CA

**University of California, San Diego, CA

New York University, New York, NY

#University of Utah, Salt Lake City, UT

††Mayo Clinic, Jacksonville, FL

‡‡University of Washington and the Veterans Affairs Northwest Network Mental Illness Research, Education, and Clinical Center

§§University of Washington, Seattle, WA

Supported by National Institute on Aging (NIA) grant (U01 AG016976). The authors recognize the support of Creighton Phelps, PhD, and Marcelle Morrison-Bogorad, PhD, from the NIA in developing the UDS and the cooperation of all Alzheimer's Disease Centers in its implementation.

Reprints: John C. Morris, MD, Alzheimer Disease Research Center, 4488 Forest Park Avenue, Suite 160, St Louis, MO 63108, (e-mail:[email protected]).

Received for publication August 31, 2006; accepted September 12, 2006

The UDS has been copyrighted: Copyright 2005-2006, University of Washington. Created and published by the Alzheimer's Disease Centers Clinical Task Force (John C. Morris, MD, Chair) and the National Alzheimer's Coordinating Center (Walter A. Kukull, PhD, Director). All rights reserved.

Alzheimer Disease & Associated Disorders20(4):p 210-216, October 2006. |DOI:10.1097/01.wad.0000213865.09806.92

Abstract

A Clinical Task Force, composed of clinical leaders from Alzheimer's Disease Centers (ADC), was convened by the National Institute on Aging to develop a uniform set of assessment procedures to characterize individuals with mild Alzheimer disease and mild cognitive impairment in comparison with nondemented aging. The resulting Uniform Data Set (UDS) defines a common set of clinical observations to be collected longitudinally on ADC participants in accordance with standard methods. The UDS was implemented at all ADCs on September 1, 2005. Data obtained with the UDS are submitted to the National Alzheimer's Coordinating Center and represent a unique and valuable source of data to support and stimulate collaborative research.

© 2006 Lippincott Williams & Wilkins, Inc.

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Alzheimer Disease & Associated Disorders20(4):210-216, October-December 2006.
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