Hostname: page-component-5cf477f64f-mgq6s Total loading time: 0 Render date: 2025-03-31T16:53:10.277Z Has data issue: false hasContentIssue false
  • English
  • Français

The Cost of Antibiotic Resistance: Effect of Resistance AmongStaphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, andPseudomonas aeruginosa on Length of Hospital Stay

Published online by Cambridge University Press: 02 January 2015

Abstract

To assess the effect of antimicrobial resistance on length of hospital stay, a case–control study compared infections due to four nosocomial pathogens. Significantly increased lengths of stay were associated with infections due to methicillin-resistantStaphylococcus aureus, extended-spectrum β-lactamase–producingKlebsiella pneumoniae, and carbapenem-resistantAcinetobacter baumannii orPseudomonas aeruginosa. Infections with resistant pathogens are associated with prolonged hospitalization.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2002

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Altman,LK. Experts see need to control antibiotics and hospital infections. New York Times March 12,1998; section A, p12.Google Scholar
2.Saurina,G,Quale,JM,Manikal,VM,Oydna,E,Landman,D.Antimicrobial-resistantKlebsiella pneumoniae, Escherichia coli, andProteus mirabilis in Brooklyn, NY: epidemiology and relation to antibiotic usage patterns.J Antimicrob Chemother2000;45:895–898.Google Scholar
3.Manikal,VM,Landman,D,Saurina,G,Oydna,E,Lal,H,Quale,J.Endemic carbapenem-resistant Acinetobacter-sp. in Brooklyn, NY: citywide prevalence, inter-institutional spread, and relation to antibiotic usage.Clin Infect Dis2000;31:101–106.CrossRefGoogle Scholar
4.Garner,JS,Jarvis,WR,Emori,TG,Horan,TC,Hughes,JM.CDC definitions for nosocomial infections, 1988.Am J Infect Control1988;16:128–140.CrossRefGoogle ScholarPubMed
5.Wakefield,DS,Helms,CM,Mori,M,Pfaller,M.Cost of nosocomial infection: relative contributions of laboratory, antibiotic, and per diem costs in seriousStaphylococcus aureus infections.Am J Infect Control1988;16:185–192.CrossRefGoogle ScholarPubMed
6.Saravolatz,LD,Markowitz,N,Arking,L,Pohlod,D,Fisher,E.Methicillin-resistantStaphylococcus aureus: epidemiologic observations during a community-acquired outbreak.Ann Intern Med1982;96:11–16.Google Scholar
7.Boyce,JM,Landry,M,Deetz,TR,DuPont,HL.Epidemiologic studies of an outbreak of methicillin-resistantStaphylococcus aureus infections.Infect Control1981;2:110–116.CrossRefGoogle ScholarPubMed
8.Abramson,MA,Sexton,DJ.Nosocomial methicillin-resistant and methi-cillin-susceptibleStaphylococcus aureus primary bacteremia: at what costs?Infect Control Hosp Epidemiol1999;20:408–411.CrossRefGoogle ScholarPubMed
9.Lautenbauch,E,Patel,JB,Bilker,WB,Edelstein,PH,Fishman,NO.Extended-spectrum beta-lactamase-producingEscherichia coli andKlebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes.Clin Infect Dis2001;32:1162–1171.CrossRefGoogle Scholar
10.Wakefield,DS,Pfaller,MA,Hammons,GT,Massanari,RM.Use of the appropriateness evaluation protocol for estimating the incremental costs associated with nosocomial infection.Med Care1987;25:481–488.Google Scholar