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Nature
  • Brief Communication
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Behavioural neuroscience

Rat navigation guided by remote control

Naturevolume 417, pages37–38 (2002)Cite this article

Free animals can be 'virtually' trained by microstimulating key areas of their brains.

Abstract

Procedures used to train laboratory animals often incorporate operant learning1 paradigms in which the animals are taught to produce particular responses to external cues (such as aural tones) in order to obtain rewards (such as food). Here we show that by removing the physical contraints associated with the delivery of cues and rewards, learning paradigms based on brain microstimulation enable conditioning approaches to be used that help to transcend traditional boundaries in animal learning. We have used this paradigm to develop a behavioural model in which an experimenter can guide distant animals in a way similar to that used to control 'intelligent' robots.

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Figure 1: Examples of guided rat navigation using brain microstimulation.

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Author information

Authors and Affiliations

  1. Department of Physiology and Pharmacology, State University of New York, Downstate Medical Centre, 450 Clarkson Avenue, Brooklyn, 11203, New York, USA

    Sanjiv K. Talwar, Shaohua Xu, Emerson S. Hawley, Shennan A. Weiss & John K. Chapin

  2. School of Biomedical Engineering, Drexel University, 3141 Chestnut Street, Philadelphia, 19104, Pennsylvania, USA

    Karen A. Moxon

Authors
  1. Sanjiv K. Talwar
  2. Shaohua Xu
  3. Emerson S. Hawley
  4. Shennan A. Weiss
  5. Karen A. Moxon
  6. John K. Chapin

Corresponding author

Correspondence toSanjiv K. Talwar.

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Competing interests

The authors declare no competing financial interests.

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