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Cholecystokinin elicits Satiety in Rats with Open Gastric Fistulas
Naturevolume 245, pages323–325 (1973)Cite this article
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Abstract
WITHIN 10 min of starting to eat, a rat stops eating1, grooms for a short period, then usually sleeps. We define this behavioural sequence as satiety: its physiological basis is unknown. Beaumont2 presented the first evidence that the presence of food in the gut is important in generating satiety signals. In 1949, Janowitz and Grossman3 confirmed Pavlov's observation4 that oesophagostomized dogs, in which no food reached the stomach or intestines, ate prolonged meals.
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Authors and Affiliations
Edward W. Bourne Behavioral Research Laboratory, Department of Psychiatry, New York Hospital, Cornell Medical Center, Westchester Division, White Plains, New York, 10605
JAMES GIBBS, ROBERT C. YOUNG & GERARD P. SMITH
- JAMES GIBBS
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- ROBERT C. YOUNG
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- GERARD P. SMITH
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GIBBS, J., YOUNG, R. & SMITH, G. Cholecystokinin elicits Satiety in Rats with Open Gastric Fistulas.Nature245, 323–325 (1973). https://doi.org/10.1038/245323a0
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