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Nature Reviews Neurology
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MULTIPLE SCLEROSIS

Mounting evidence for a multiple sclerosis prodrome

Nature Reviews Neurologyvolume 15pages689–690 (2019)Cite this article

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A new study provides direct biological evidence for a prodromal phase of multiple sclerosis (MS), with implications for studying disease aetiology and underscoring the limitations of therapies that solely target inflammation. The findings also suggest an opportunity to apply secondary prevention strategies at the very earliest stages of the disease.

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Acknowledgements

This article was supported (in part) by a Manitoba Research Chair from Research Manitoba, and the Waugh Family Chair in Multiple Sclerosis.

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  1. Departments of Internal Medicine and Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada

    Ruth Ann Marrie

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  1. Ruth Ann Marrie

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Correspondence toRuth Ann Marrie.

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Marrie, R.A. Mounting evidence for a multiple sclerosis prodrome.Nat Rev Neurol15, 689–690 (2019). https://doi.org/10.1038/s41582-019-0283-0

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