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Sequence of aDrosophila segmentation gene: protein structure homology with DNA-binding proteins
Naturevolume 310, pages25–31 (1984)Cite this article
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Abstract
Mutations in thefushi tarazu (ftz) locus ofDrosophila result in embryos with half the usual number of body segments. The sequences of the wild-type gene, a temperature-sensitive allele and a dominant mutant allele are presented. A portion of the conserved protein domain present inftz and several homoeotic genes resembles the DNA-binding region of prokaryotic DNA-binding proteins, and is also similar to products of the yeast mating-type locus.
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Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Campus Box 347, Boulder, Colorado, 80309, USA
Allen Laughon & Matthew P. Scott
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Laughon, A., Scott, M. Sequence of aDrosophila segmentation gene: protein structure homology with DNA-binding proteins.Nature310, 25–31 (1984). https://doi.org/10.1038/310025a0
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