- Wee Pheng Goh ORCID:orcid.org/0000-0002-4742-16841,
- Xiaohui Tao1,
- Ji Zhang1,
- Jianming Yong2,
- Wenping Zhang3 &
- …
- Haoran Xie4
227Accesses
Abstract
The rapid increase in the volume and variety of data poses a challenge to safe drug prescription for the dentist. The increasing number of patients that take multiple drugs further exerts pressure on the dentist to make the right decision at point-of-care. Hence, a robust decision support system will enable dentists to make decisions on drug prescription quickly and accurately. Based on the assumption that similar drug pairs have a higher similarity ratio, this paper suggests an innovative approach to obtain the similarity ratio between the drug that the dentist is going to prescribe and the drug that the patient is currently taking. We conducted experiments to obtain the similarity ratios of both positive and negative drug pairs, by using feature vectors generated from term similarities and word embeddings of biomedical text corpus. This model can be easily adapted and implemented for use in a dental clinic to assist the dentist in deciding if a drug is suitable for prescription, taking into consideration the medical profile of the patients. Experimental evaluation of our model’s association of the similarity ratio between two drugs yielded a superiorF score of 89%. Hence, such an approach, when integrated within the clinical work flow, will reduce prescription errors and thereby increase the health outcomes of patients.
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Lieber, N.S.R., Ribeiro, E.: Adverse drug reactions leading children to the emergency department. Rev. Bras. Epidemiol.15, 265–274 (2012)
Brown, A.S., Patel, C.J.: Meshdd: literature-based drug-drug similarity for drug repositioning. J. Am. Med. Inf. Assoc.27, 1–5 (2016)
Bui, Q., Sloot, P., van Mulligen, E., Kors, J.: A novel feature-based approach to extract drug-drug interactions from biomedical text. BioInformatics30(23), 3365–3371 (2014)
Casillas, A., Pérez, A., Oronoz, M., Gojenola, K., Santiso, S.: Learning to extract adverse drug reaction events from electronic health records in spanish. Expert Syst. Appl.61, 235–245 (2016)
Goh, W.P., Tao, X., Zhang, J., Yong, J.: Mining drug properties for decision support in dental clinics. In: Kim, J., Shim, K., Cao, L., Lee, J.-G., Lin, X., Moon, Y.-S. (eds.) PAKDD 2017, Part 2, pp. 375–387. Springer, Berlin (2017)
Wu, H.-Y., Chiang, C.-W., Li, L.: Text mining for drug–drug interaction. Methods Mol. Biol.1159, 47–75 (2014)
Bokharaeian, B., Diaz, A., Chitsaz, H.: Enhancing extraction of drug-drug interaction from literature using neutral candidates, negation, and clause dependency. PLoS ONE11(10), 1–20 (2016)
Li, A., Zang, Q., Sun, D., Wang, M.: A text feature-based approach for literature mining of lncrna-protein interactions. Neurocomput.206(C), 73–80 (2016).https://doi.org/10.1016/j.neucom.2015.11.110
Tari, L., Anwar, S., Liang, S., Baral, J.C.: Discovering drug-drug interactions a text-mining and reasoning approach based on properties of drug metabolism. Bioinformatics26(18), 547–553 (2010)
Yan, S., Jiang, X., Chen, Y.: Text mining driven drug–drug interaction detection. In: 2013 IEEE International Conference on Bioinformatics and Biomedicine, pp. 349–354 (2013)
Goh, W.P., Tao, X., Zhang, J., Yong, J.: Decision support systems for adoption in dental clinics: a survey. Knowl. Based Syst.104, 195–206 (2016)
Park, S.G., Lee, S., Kim, M.-K., Kim, H.-G.: Shared decision support system on dental restoration. Expert Syst. Appl.39(14), 11775–11781 (2012)
Smart, P.R., Sadraie, M.: Applications and uses of dental ontologies. In: Proceedings of the 2012 IADIS International Conference, pp. 499–504 (2012)
Bhatia, A., Singh, R.: Using bayesian network as decision making system tool for deciding treatment plan for dental caries. J. Acad. Ind. Res.2(2), 93–96 (2013)
Bessani, M., Lins, E., Delbem, A., Maciel, C.: Construction of a clinical decision support system for dental caries management using BN. In: Brazilian Congress on Biomedical Engineering, pp. 517–520 (2014)
Dechanont, S., Maphanta, S., Butthum, B., Kongkaew, C.: Hospital admissions/visits associated with drug-drug interactions: a systematic review and meta-analysis. Pharmacoepidemiol. Drug Saf.23(5), 489–497 (2014)
Cai, Y., Au Yeung, C.-m., Leung, H.-f.: Knowledge representation on the web. In: Fuzzy Computational Ontologies in Contexts: Formal Models of Knowledge Representation with Membership Degree and Typicality of Objects, and Their Applications, pp. 15–21. Springer, Berlin (2012)
Ayvaz, S., Horn, J., Hassanzadeh, O., Zhu, Q., Stan, J., Tatonetti, N.P., Vilar, S., Brochhausen, M., Samwald, M., Rastegar-Mojarad, M., Dumontier, M., Boyce, R.D.: Toward a complete dataset of drug-drug interaction information from publicly available sources. Biomed. Inf.55, 206–217 (2015)
Sen, S., Swoap, A.B., Li, Q., Boatman, B., Dippenaar, I., Gold, R., Ngo, M., Pujol, S., Jackson, B., Hecht, B.: Cartograph: unlocking spatial visualization through semantic enhancement. In: Proceedings of the 22nd International Conference on Intelligent User Interfaces, IUI’17, pp. 179–190. ACM, New York (2017)
Mikolov, T., Chen, K., Corrado, G., Dean, J.: Efficient estimation of word representations in vector space. CoRRarXiv:1301.3781
Drozd, A., Gladkova, A., Matsuoka, S.: Word embeddings, analogies, and machine learning: Beyond king – man + woman = queen. In: Proceedings of COLING 2016, the 26th International Conference on Computational Linguistics, pp. 3519–3530 (2016)
Mikolov, T., Sutskever, I., Chen, K., Corrado, G.S., Dean, J.: Distributed representations of words and phrases and their compositionality. In: Burges, C.J.C., Bottou, L., Welling, M., Ghahramani, Z., Weinberger, K.Q. (eds.) Advances in Neural Information Processing Systems, vol. 26, pp. 3111–3119. Curran Associates Inc., Red Hook (2013)
Zhang, Y., Jatowt, A., Tanaka, K.: Towards understanding word embeddings: automatically explaining similarity of terms. In: 2016 IEEE International Conference on Big Data (Big Data), pp. 823–832 (2016)
Acknowledgements
This research is partially supported by Glory Dental Surgery (Roxy Square) Pte Ltd, Singapore (http://glory.sg), and undertaken collaboratively with their panel of dentists. The authors would like to thank the reviewers, the handling editor and the Editor-in-Chief for their constructive comments on the manuscript. We would also like to thank Dr Elizabeth Goh (e-mail: eg@glory.sg) for enriching the authors’ understanding of dentists’ requirements and for proof-reading the manuscript.
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Authors and Affiliations
Faculty of Health, Engineering and Sciences, University of Southern Queensland, Toowoomba, Australia
Wee Pheng Goh, Xiaohui Tao & Ji Zhang
Faculty of Business, Education, Law and Arts, University of Southern Queensland, Toowoomba, Australia
Jianming Yong
School of Information, Renmin University, Beijing, China
Wenping Zhang
Department of Mathematics and Information Technology, The Education University of Hong Kong, Hong Kong SAR, China
Haoran Xie
- Wee Pheng Goh
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- Xiaohui Tao
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Correspondence toWee Pheng Goh orXiaohui Tao.
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This paper is an extension version of the PAKDD 2017 Long Presentation paper “Mining Drug Properties for Decision Support in Dental Clinics”.
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Goh, W.P., Tao, X., Zhang, J.et al. Drug prescription support in dental clinics through drug corpus mining.Int J Data Sci Anal6, 341–349 (2018). https://doi.org/10.1007/s41060-018-0149-3
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