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Measurement of Myocardial Structure: 3D Structure Tensor Analysis of High Resolution MRI Quantitatively Compared to DT-MRI

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Abstract

The ventricular myocardium has a structure of branching laminae through which course regularly orientated fibers, an architecture important in excitation and contraction. DT-MRI is used to measure the fiber and laminar orientations. We quantify the performance of DT-MRI and structure tensor (ST) analysis of 3D high resolution MRI in five rat hearts and validate these against manual measurements. The ST and DT data are more similar for measures of the fiber orientation than laminar orientation. The average angle differences of elevation angles are 2.3±27.2˚, R = 0.57 for the fiber, 3.62±36.2˚, R = 0.24 for the laminae and 10.7±37.9˚, R = 0.32 for the laminae normal. The difference between DT and manually measured laminar orientation is 17±15˚ for DT and 5±10˚ for ST. DT and ST are comparable measures of the fiber orientation but ST is a better measure of myolaminar orientation.

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Author information

Authors and Affiliations

  1. Multidisciplinary Cardiovascular Research Centre, University of Leeds, UK

    Stephen Gilbert & Olivier Bernus

  2. NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, UK

    Aleksandra Radjenovic

  3. L’Institut de ryhtmologie et modélisation cardiaque, Unité Inserm 1045, Centre de Recherche Cardio-Thoracique, Université Bordeaux Segalen, 33076, Bordeaux, France

    Stephen Gilbert & Olivier Bernus

  4. Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand

    Mark Trew & Bruce Smaill

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  1. Stephen Gilbert

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  2. Mark Trew

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  3. Bruce Smaill

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  4. Aleksandra Radjenovic

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  5. Olivier Bernus

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Editor information

Editors and Affiliations

  1. Department of Information and Communication, Universitat Pompeu Fabra, Roc Boronat 138, 08018, Barcelona, Spain

    Oscar Camara

  2. Siemens Corporate Research, 755 College Road East, 08540, Princeton, NJ, USA

    Tommaso Mansi

  3. Sunnybrook Health Science Centre, Department of Medical Biophsics, University of Toronto, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada

    Mihaela Pop

  4. School of Medicine, Department of Medical Engineering and Physics, King’s College Hospital, Faraday Building, SE5 9RS, Lonon, UK

    Kawal Rhode

  5. INRIA Sophia Antipolis, Asclepios Research Project, 2004 Route des Lucioles, BP 03, 06902, Sophia Antipolis Cedex, France

    Maxime Sermesant

  6. Faculty of Medical and Halth Sciences, Department of Anatomy with Radiology, University of Auckland, Grafton Campus, Building 502, Auckland, New Zealand

    Alistair Young

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© 2013 Springer-Verlag Berlin Heidelberg

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Gilbert, S., Trew, M., Smaill, B., Radjenovic, A., Bernus, O. (2013). Measurement of Myocardial Structure: 3D Structure Tensor Analysis of High Resolution MRI Quantitatively Compared to DT-MRI. In: Camara, O., Mansi, T., Pop, M., Rhode, K., Sermesant, M., Young, A. (eds) Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges. STACOM 2012. Lecture Notes in Computer Science, vol 7746. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36961-2_24

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