In this paper we show how we used multiple large knowledge sources to construct a much smaller knowledge graph that is focussed on single disease (in our case major depression disorder). Such a disease-centric knowledge-graph makes it more convenient for doctors (in our case psychiatric doctors) to explore the relationship among various knowledge resources and to answer realistic clinical queries.

This work is partially supported by the Dutch national project COMMIT, the international cooperation project No. 61420106005 funded by National Natural Science Foundation of China, and the NWO-funded Project Re-Search. The fourth author is funded by the China Scholarship Council.

Authors and Affiliations

1. VU University Amsterdam, Amsterdam, The Netherlands

   Zhisheng Huang, Frank van Harmelen & Qing Hu

2. Beijing Anding Hospital, Beijing, China

   Jie Yang

3. College of Computer Science and Technology, Wuhan Univesity of Science and Technology, Wuhan, China

   Qing Hu

Corresponding author

Correspondence toZhisheng Huang.

Editors and Affiliations

1. Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

   Annette ten Teije

2. Medical University of Vienna, Vienna, Austria

   Christian Popow

3. University of Pennsylvania, Philadelphia, Pennsylvania, USA

   John H. Holmes

4. University of Pavia, Pavia, Italy

   Lucia Sacchi

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