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Interpolation and Averaging of Multi-Compartment Model Images

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Abstract

Multi-compartment diffusion models (MCM) are increasingly used to characterize the brain white matter microstructure from diffusion MRI. We address the problem of interpolation and averaging of MCM images as a simplification problem based on spectral clustering. As a core part of the framework, we propose novel solutions for the averaging of MCM compartments. Evaluation is performed both on synthetic and clinical data, demonstrating better performance for the “covariance analytic” averaging method. We then present an MCM template of normal controls constructed using the proposed interpolation.

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Author information

Authors and Affiliations

  1. VISAGES: INSERM U746, CNRS UMR6074, INRIA, Univ. of Rennes I, Rennes, France

    Renaud Hédouin, Olivier Commowick & Christian Barillot

  2. CRL, Children’s Hospital Boston, Harvard Medical School, Boston, USA

    Aymeric Stamm

Authors
  1. Renaud Hédouin

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  2. Olivier Commowick

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  3. Aymeric Stamm

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  4. Christian Barillot

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Editor information

Editors and Affiliations

  1. TU München, Garching, Germany

    Nassir Navab

  2. Lehrstuhl Informatik 5, University of Erlangen-Nuremberg, Erlangen, Germany

    Joachim Hornegger

  3. Brigham and Women's Hospital, Boston, Massachusetts, USA

    William M. Wells

  4. University of Sheffield, Sheffield, Suffolk, United Kingdom

    Alejandro Frangi

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© 2015 Springer International Publishing Switzerland

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Hédouin, R., Commowick, O., Stamm, A., Barillot, C. (2015). Interpolation and Averaging of Multi-Compartment Model Images. In: Navab, N., Hornegger, J., Wells, W., Frangi, A. (eds) Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2015. MICCAI 2015. Lecture Notes in Computer Science(), vol 9350. Springer, Cham. https://doi.org/10.1007/978-3-319-24571-3_43

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