• Adler A, Spencer S (1991) Effect of light on endogenous ligands carried by interphotoreceptor retinoid-binding protein. Exp Eye Res 53:337–346

  Article CAS PubMed  Google Scholar 

• Ala-Laurila P, Kolesnikov A, Crouch R et al (2006) Visual cycle: dependence of retinol production and removal on photoproduct decay and cell morphology. J Gen Physiol 128:153–169

  Article CAS PubMed  Google Scholar 

• Bunt-Milam A, Saari J (1983) Immunocytochemical localization of two retinoid-binding proteins in vertebrate retina. J Cell Biol 97:703–712

  Article CAS PubMed  Google Scholar 

• Bustamante J, Ziari S, Ramirez R, Tsin AT (1995) Retinyl ester hydrolase and the visual cycle in the chicken eye. Am J Physiol 269:R1346–R1350

  CAS PubMed  Google Scholar 

• Carter-Dawson L, Burroughs M (1992a) Interphotoreceptor retinoid-binding protein in the cone matrix sheath. Electron microscopic immunocytochemical localization. Invest Ophthalmol Vis Sci 33:1584–1588

  CAS PubMed  Google Scholar 

• Carter-Dawson L, Burroughs M (1992b) Interphotoreceptor retinoid-binding protein in the Golgi apparatus of monkey foveal cones. Electron microscopic immunocytochemical localization. Invest Ophthalmol Vis Sci 33:1589–1594

  CAS PubMed  Google Scholar 

• Chen Y, Saari J, Noy N (1993) Interactions of all-trans-retinol and long-chain fatty acids with interphotoreceptor retinoid-binding protein. Biochemistry 32:11311–11318

  Article CAS PubMed  Google Scholar 

• Crouch R, Katz S (1980) Effect of retinal Isomers on the VER and ERG of vitamin A-deprived rats. Vision Res 20:109–115

  Article CAS PubMed  Google Scholar 

• Crouch R, Hazard E, Lind T et al (1992) Interphotoreceptor retinoid-binding protein and alpha-tocopherol preserve the isomeric and oxidation state of retinol. Photochem Photobiol 56:251–255

  Article CAS PubMed  Google Scholar 

• Das S, Bhardwaj N, Kjeldbye H et al (1992) Müller cells of chicken retina synthesize 11-cis-retinol. Biochem J 285(Pt 3):907–913

  CAS PubMed  Google Scholar 

• den Hollander A, McGee T, Ziviello C et al (2009) A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa. Invest Ophthalmol Vis Sci 30(4):1864–1872

  Google Scholar 

• Edwards R, Adler A (2000) IRBP enhances removal of 11-cis-retinaldehyde from isolated RPE membranes. Exp Eye Res 70:235–245

  Article CAS PubMed  Google Scholar 

• Fong S, Liou G, Landers R et al (1984) Purification and characterization of a retinol-binding glycoprotein synthesized and secreted by bovine neural retina. J Biol Chem 259:6534–6542

  CAS PubMed  Google Scholar 

• Gonzalez-Fernandez F, Healy J (1990) Early expression of the gene for interphotoreceptor retinol-binding protein during photoreceptor differentiation suggests a critical role for the interphotoreceptor matrix in retinal development. J Cell Biol 111:2775–2784

  Article CAS PubMed  Google Scholar 

• Ho M, Massey J, Pownall H et al (1989) Mechanism of vitamin A movement between rod outer segments, interphotoreceptor retinoid-binding protein, and liposomes. J Biol Chem 264:928–935

  CAS PubMed  Google Scholar 

• Hood D, Hock P (1973) Recovery of cone receptor activity in the frog’s isolated retina. Vision Res 13:1943–1951

  Article CAS PubMed  Google Scholar 

• Johnson L, Hageman G, Blanks J (1986) Interphotoreceptor matrix domains ensheath vertebrate cone photoreceptor cells. Invest Ophthalmol Vis Sci 27:129–135

  CAS PubMed  Google Scholar 

• Jones G, Crouch R, Wiggert B et al (1989) Retinoid requirements for recovery of sensitivity after visual-pigment bleaching in isolated photoreceptors. Proc Natl Acad Sci USA 86:9606–9610

  Article CAS PubMed  Google Scholar 

• Liou G, Fei Y, Peachey N et al (1998) Early onset photoreceptor abnormalities induced by targeted disruption of the interphotoreceptor retinoid-binding protein gene. J Neurosci 18:4511–4520

  CAS PubMed  Google Scholar 

• Loew A, Gonzalez-Fernandez F (2002) Crystal structure of the functional unit of interphotoreceptor retinoid binding protein. Structure 10:43–49

  Article CAS PubMed  Google Scholar 

• Mata N, Radu R, Clemmons R et al (2002) Isomerization and oxidation of vitamin A in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight. Neuron 36:69–80

  Article CAS PubMed  Google Scholar 

• Mata N, Ruiz A, Radu R (2005) Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol. Biochemistry 44:11715–11721

  Article CAS PubMed  Google Scholar 

• Okajima T, Wiggert B, Chader G (1994) Retinoid processing in retinal pigment epithelium of toad (Bufo marinus). J Biol Chem 269:21983–21989

  CAS PubMed  Google Scholar 

• Palczewski K, Van Hooser J, Garwin G (1999) Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin. Biochemistry 38:12012–12019

  Article CAS PubMed  Google Scholar 

• Ripps H, Peachey N, Xu X (2000) The rhodopsin cycle is preserved in IRBP ``knockout’ mice despite abnormalities in retinal structure and function. Vis Neurosci 17:97–105

  Article CAS PubMed  Google Scholar 

• Saari J, Teller D, Crabb J (1985) Properties of an interphotoreceptor retinoid-binding protein from bovine retina. J Biol Chem 260:195–201

  CAS PubMed  Google Scholar 

• Shaw N, Noy N (2001) Interphotoreceptor retinoid-binding protein contains three retinoid binding sites. Exp Eye Res 72:183–190

  Article CAS PubMed  Google Scholar 

• Uehara F, Matthes M, Yasumura D et al (1990) Light-evoked changes in the interphotoreceptor matrix. Science 248:1633–1636

  Article CAS PubMed  Google Scholar 

• Wald G (1935) Carotenoids and the visual cycle. J Gen Physiol 19:351–371

  Article CAS PubMed  Google Scholar 

• Wald G (1955) The photoreceptor process in vision. Am J Ophthalmol 40:18–41

  CAS PubMed  Google Scholar 

• Wenzel A, Grimm C, Samardzija M et al (2005) Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog Retin Eye Res 24:275–306

  Article CAS PubMed  Google Scholar 

• Wu Q, Blakeley L, Cornwall M et al (2007) Interphotoreceptor retinoid-binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments. Biochemistry 46:8669–8679

  Article CAS PubMed  Google Scholar 

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