• Arevalo J. C., Waite J., Rajagopal R., Beyna M., Chen Z. Y., Lee F. S. and Chao M. V., 2006, Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination.Neuron50, 549–59.

  Article PubMed CAS  Google Scholar 

• Chaum E., 2003, Retinal neuroprotection by growth factors: a mechanistic perspective.J Cell Biochem88, 57–75.

  Article PubMed CAS  Google Scholar 

• Chen W. G., West A. E., Tao X., Corfas G., Szentirmay M. N., Sawadogo M., Vinson C. and Greenberg M. E., 2003, Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons.J Neurosci23, 2572–81.

  PubMed CAS  Google Scholar 

• Cheng L., Sapieha P., Kittlerova P., Hauswirth W. W. and Di Polo A., 2002, TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo.J Neurosci22, 3977–86.

  PubMed CAS  Google Scholar 

• Fryer H. J., Wolf D. H., Knox R. J., Strittmatter S. M., Pennica D., O’Leary R. M., Russell D. S. and Kalb R. G., 2000, Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway.J Neurochem74, 582–95.

  Article PubMed CAS  Google Scholar 

• Harada T., Harada C., Kohsaka S., Wada E., Yoshida K., Ohno S., Mamada H., Tanaka K., Parada L. F. and Wada K., 2002, Microglia-Muller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration.J Neurosci22, 9228–36.

  PubMed CAS  Google Scholar 

• Harada T., Harada C., Nakayama N., Okuyama S., Yoshida K., Kohsaka S., Matsuda H. and Wada K., 2000, Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration.Neuron26, 533–41.

  Article PubMed CAS  Google Scholar 

• Kalb R., 2005, The protean actions of neurotrophins and their receptors on the life and death of neurons.Trends Neurosci28, 5–11.

  Article PubMed CAS  Google Scholar 

• Kim H. J., Hwang J. J., Behrens M. M., Snider B. J., Choi D. W. and Koh J. Y., 2003, TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture.Neurobiol Dis14, 110–9.

  Article PubMed CAS  Google Scholar 

• Lenzi L., Coassin M., Lambiase A., Bonini S., Amendola T. and Aloe L., 2005, Effect of exogenous administration of nerve growth factor in the retina of rats with inherited retinitis pigmentosa.Vision Res45, 1491–500.

  Article PubMed CAS  Google Scholar 

• Meyer-Franke A., Wilkinson G. A., Kruttgen A., Hu M., Munro E., Hanson M. G., Jr., Reichardt L. F. and Barres B. A., 1998, Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons.Neuron21, 681–93.

  Article PubMed CAS  Google Scholar 

• Muragaki Y., Chou T. T., Kaplan D. R., Trojanowski J. Q. and Lee V. M., 1997, Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptors.J Neurosci17, 530–42.

  PubMed CAS  Google Scholar 

• Nag T. C. and Wadhwa S., 1999, Neurotrophin receptors (Trk A, Trk B, and Trk C) in the developing and adult human retina.Brain Res Dev Brain Res117, 179–89.

  Article PubMed CAS  Google Scholar 

• Nakamura K., Harada C., Okumura A., Namekata K., Mitamura Y., Yoshida K., Ohno S., Yoshida H. and Harada T., 2005, Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse.Mol Vis11, 1229–35.

  PubMed CAS  Google Scholar 

• Patapoutian A., Backus C., Kispert A. and Reichardt L. F., 1999, Regulation of neurotrophin-3 expression by epithelial-mesenchymal interactions: the role of Wnt factors.Science283, 1180–83.

  Article PubMed CAS  Google Scholar 

• Rohrer B., Matthes M. T., LaVail M. M. and Reichardt L. F., 2003, Lack of p75 receptor does not protect photoreceptors from light-induced cell death.Exp Eye Res76, 125–9.

  Article PubMed CAS  Google Scholar 

• Roux P. P., Bhakar A. L., Kennedy T. E. and Barker P. A., 2001, The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway.J Biol Chem276, 23097–104.

  Article PubMed CAS  Google Scholar 

• Taylor S., Srinivasan B., Wordinger R. J. and Roque R. S., 2003, Glutamate stimulates neurotrophin expression in cultured Muller cells.Brain Res Mol Brain Res111, 189–97.

  Article PubMed CAS  Google Scholar 

• Timmusk T., Palm K., Metsis M., Reintam T., Paalme V., Saarma M. and Persson H., 1993, Multiple promoters direct tissue-specific expression of the rat BDNF gene.Neuron10, 475–89.

  Article PubMed CAS  Google Scholar 

• Tuli R., Tuli S., Nandi S., Huang X., Manner P. A., Hozack W. J., Danielson K. G., Hall D. J. and Tuan R. S., 2003, Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk.J Biol Chem278, 41227–36.

  Article PubMed CAS  Google Scholar 

• von Schack D., Casademunt E., Schweigreiter R., Meyer M., Bibel M. and Dechant G., 2001, Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system.Nat Neurosci4, 977–8.

  Article  Google Scholar 

• Wahlin K. J., Adler R., Zack D. J. and Campochiaro P. A., 2001, Neurotrophic signaling in normal and degenerating rodent retinas.Exp Eye Res73, 693–701.

  Article PubMed CAS  Google Scholar 

• Wahlin K. J., Campochiaro P. A., Zack D. J. and Adler R., 2000, Neurotrophic factors cause activation of intracellular signaling pathways in Muller cells and other cells of the inner retina, but not photoreceptors.Invest Ophthalmol Vis Sci41, 927–36.

  PubMed CAS  Google Scholar 

• Wen R., Song Y., Cheng T., Matthes M. T., Yasumura D., LaVail M. M. and Steinberg R. H., 1995, Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina.J Neurosci15, 7377–85.

  PubMed CAS  Google Scholar 

• Wu H., Friedman W. J. and Dreyfus C. F., 2004, Differential regulation of neurotrophin expression in basal forebrain astrocytes by neuronal signals.J Neurosci Res76, 76–85.

  Article PubMed CAS  Google Scholar 

• Yu D. Y., Cringle S., Valter K., Walsh N., Lee D. and Stone J., 2004, Photoreceptor death, trophic factor expression, retinal oxygen status, and photoreceptor function in the P23H rat.Invest Ophthalmol Vis Sci45, 2013–19.

  Article PubMed  Google Scholar 

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