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Summary
Tremor dose-response curves were determined for mice dosed with the ryegrass neurotoxin lolitrem B, and the tremorgenic mycotoxin aflatrem. A family of characteristic curves was revealed for each tremorgen, with lolitrem B eliciting a sustained tremor response persisting for over 24 h.
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Gallagher, R.T., White, E.P., and Mortimer, P.H., N.Z. Vet. J.29 (1981) 189.
Gallagher, R.T., Campbell, A.G., Hawkes, A.D., Holland, P.T., McGaveston, D.A., Pansier, E.A., and Harvey, I.C., N.Z. Vet. J.30 (1982) 183.
Gallagher, R.T., Hawkes, A.D., and Stewart, J.M., J. Chromat.321 (1985) 217.
Gallagher, R.T., and Hawkes, A.D., N.Z. J. agric. Res.28 (1985) 427.
Gallagher, R.T., Hawkes, A.D., Steyn, P.S., and Vleggaar, R., J. Chem. Soc. Chem. Commun. (Lond.) (1984) 614.
Keogh, R.G., N.Z. J. expl Agric.1 (1973) 55.
Gallagher, R.T., Keogh, R.G., Latch, G.C.M. and Reid, C.S.W., N.Z. J. agric. Res.20 (1977) 431.
Mantle, P.G., and Penny, R.C., in: The Veterinary Annual, 21st Issue, p. 51. Eds C.S.G. Grunsell and F.W.G. Hill. Scientechnica, J. Wright and Sons, Bristol, England 1981.
Mortimer, P.H., Young, P.W., and Dimenna, M.E., Proc. N.Z. Soc. Anim. Prod.44 (1984) 181.
Gallagher, R.T., in: Proc. Eighth Congress International Society for Human and Animal Mycology, February 1982, p. 469. Ed. M. Baxter, Massey University, Palmerston North, New Zealand 1983.
Munday, B.L., Monkhouse, I.M., and Gallagher, R.T., Aust. Vet. J.62 (1985) 207.
Aasen, A.J., Culvenor, C.J., Finnie, E.P., Kellock, A.W., and Smith, L.W., Aust. J. agric. Res.20 (1969) 71.
Shreeve, B.J., Patterson, D.S.P., Roberts, B.A., MacDonald, S.M., and Wood, E.N., Vet. Rec.103 (1978) 209.
Lanigan, G.W., Payne, A.L., and Cockrum, P.A., Aust. J. expl Biol. med. Sci.57 (1979) 31.
Wilson, B.J., and Wilson, C.H., Science144 (1964) 177.
Gallagher, R.T., and Wilson, B.J., Mycopathologia66 (1978) 183.
Gallagher, R.T., Clardy, J., and Wilson, B.J., Tetrahedron Lett.21 (1980) 239.
Cole, R.J., Dorner, J.W., Springer, J.P., and Cox, R.H., J. Agric. Food Chem.29 (1981) 293.
Kelly, D.M., and Naylor, R.J., Eur. J. Pharmac.27 (1974) 14.
Everett, G.M., Blockus, L.E., and Shepperd, I.M., Science124 (1956) 79.
Jenden, D.J., in: Selected Pharmacological Testing Methods, vol. 3, p. 337. Ed. A. Burger, Medicinal Research Series, Marcel Dekker Inc., New York 1968.
Cole, R.J., J. Food Protec.44 (1981) 715.
Betina, V., in: Mycotoxins: Production, Isolation, Separation and Purification, p. 415. Ed. V. Betina. Elsevier, Amsterdam 1984.
Gallagher, R.T., and Hawkes, A.D., J. Chromat.322 (1985) 159.
Caujolle, F.M.E., Caujolle, D.H., Cros, S.B., and Calvet, M.-M.J., Ann. N.Y. Acad. Sci.141 (1967) 110.
David, N.A., A. Rev. Pharmac.12 (1972) 353.
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Ruakura Animal Research Station, Ministry of Agriculture and Fisheries, Private Bag, Hamilton, New Zealand
R. T. Gallagher & A. D. Hawkes
- R. T. Gallagher
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- A. D. Hawkes
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Gallagher, R.T., Hawkes, A.D. The potent tremorgenic neurotoxins lolitrem B and aflatrem: A comparison of the tremor response in mice.Experientia42, 823–825 (1986). https://doi.org/10.1007/BF01941539
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