1. Maret W (2013) Zinc and the zinc proteome. In: Banci L (ed) Metallomics and the cell. Springer, Dordrecht, pp 479–501

   Chapter  Google Scholar 

2. Prashanth L, Kattapagari KK, Chitturi RT, Baddam VRR, Prasad LK (2015) A review on role of essential trace elements in health and disease. J NTR Univ Health Sci 4(2):75

   Article  Google Scholar 

3. Blindauer CA (2015) Advances in the molecular understanding of biological zinc transport. Chem Commun 51(22):4544–4563

   Article CAS  Google Scholar 

4. Wang D, Fierke CA (2013) The BaeSR regulon is involved in defense against zinc toxicity inE. coli. Metallomics 5:372–383

   Article CAS PubMed PubMed Central  Google Scholar 

5. Abu Kwaik Y, Bumann D (2013) Microbial quest for food in vivo: ‘nutritional virulence’as an emerging paradigm. Cell Microbiol 15(6):882–890

   Article CAS PubMed  Google Scholar 

6. Cerasi M, Ammendola S, Battistoni A (2013) Competition for zinc binding in the host-pathogen interaction. Front Cell Infect Microbiol 3:108

   Article PubMed PubMed Central  Google Scholar 

7. Porcheron G, Garénaux A, Proulx J, Sabri M, Dozois CM (2013) Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence. In: Veyrier F, Cellier M (eds) Metal economy in host-microbe interactions. Frontiers Media SA, Lausanne, pp 172–195

   Google Scholar 

8. Nies DH (2007) How cells control zinc homeostasis. Science 317:1695–1696

   Article CAS PubMed  Google Scholar 

9. Kambe T, Yamaguchi-Iwai Y, Sasaki R, Nagao M (2004) Overview of mammalian zinc transporters. Cell Mol Life Sci 61:49–68

   Article CAS PubMed  Google Scholar 

10. Nadadur SS, Srirama K, Mudipalli A (2008) Iron transport and homeostasis mechanisms: their role in health and disease. Indian J Med Res 128:533–544

    CAS PubMed  Google Scholar 

11. Dean P, Major P, Nakjang S, Hirt RP, Embley TM (2014) Transport proteins of parasitic protists and their role in nutrient salvage. Front Plant Sci 5:153

    Article PubMed PubMed Central  Google Scholar 

12. North M, Steffen J, Loguinov AV, Zimmerman GR, Vulpe CD, Eide DJ (2012) Genome-wide functional profiling identifies genes and processes important for zinc-limited growth ofSaccharomyces cerevisiae. PLoS Genet 8(6):e1002699

    Article CAS PubMed PubMed Central  Google Scholar 

13. Nies DH, Silver S (1995) Ion efflux systems involved in bacterial metal resistances. J Ind Microbiol 14:186–199.https://doi.org/10.1007/BF01569902

    Article CAS PubMed  Google Scholar 

14. Kolaj-Robin O, Russell D, Hayes KA, Pembroke JT, Soulimane T (2015) Cation diffusion facilitator family: structure and function. FEBS Lett 589(12):1283–1295

    Article CAS PubMed  Google Scholar 

15. Montanini B, Blaudez D, Jeandroz S, Sanders D, Chalot M (2007) Phylogenetic and functional analysis of the cation diffusion facilitator (CDF) family: improved signature and prediction of substrate specificity. BMC Genomics 8(1):107

    Article PubMed PubMed Central  Google Scholar 

16. Palmiter RD, Huang L (2004) Efflux and compartmentalization of zinc by members of the SLC30 family of solute carriers. Pflugers Arch 447(5):744–751

    Article CAS PubMed  Google Scholar 

17. Kambe T, Tsuji T, Hashimoto A, Itsumura N (2015) The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism. Physiol Rev 95(3):749–784

    Article CAS PubMed  Google Scholar 

18. Nies DH (2003) Efflux-mediated heavy metal resistance in prokaryotes. FEMS Microbiol Rev 27(2-3):313–339

    Article CAS PubMed  Google Scholar 

19. Cubillas C, Vinuesa P, Tabche ML, García-de los Santos A (2013) Phylogenomic analysis of cation diffusion facilitator proteins uncovers Ni²⁺/Co²⁺ transporters. Metallomics 5(12):1634–1643

    Article CAS PubMed  Google Scholar 

20. Cragg RA, Christie GR, Phillips SR, Russi RM, Küry S, Mathers JC et al (2002) A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane. J Biol Chem 277(25):22789–22797

    Article CAS PubMed  Google Scholar 

21. Kambe T, Narita H, Yamaguchi-Iwai Y, Hirose J, Amano T, Sugiura N et al (2002) Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic β cells. J Biol Chem 277(21):19049–19055

    Article CAS PubMed  Google Scholar 

22. Li L, Kaplan J (2001) The yeast gene MSC2, a member of the cation diffusion facilitator family, affects the cellular distribution of zinc. J Biol Chem 276(7):5036–5043

    Article CAS PubMed  Google Scholar 

23. Gaither LA, Eide DJ (2001) Eukaryotic zinc transporters and their regulation. In: Zinc biochemistry, physiology, and homeostasis. Springer, Dordrecht, pp 65–84

    Chapter  Google Scholar 

24. Gustin JL, Zanis MJ, Salt DE (2011) Structure and evolution of the plant cation diffusion facilitator family of ion transporters. BMC Evol Biol 11(1):76

    Article CAS PubMed PubMed Central  Google Scholar 

25. Hoch E, Lin W, Chai J, Hershfinkel M, Fu D, Sekler I (2012) Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn²⁺ over Cd²⁺ selectivity. Proc Natl Acad Sci 109(19):7202–7207

    Article CAS PubMed PubMed Central  Google Scholar 

26. Lee SM, Grass G, Haney CJ, Fan B, Rosen BP, Anton A et al (2002) Functional analysis of theEscherichia coli zinc transporter ZitB. FEMS Microbiol Lett 215(2):273–278

    Article CAS PubMed  Google Scholar 

27. Menezes CB, Frasson AP, Tasca T (2016) Trichomoniasis-are we giving the deserved attention to the most common non-viral sexually transmitted disease worldwide? Microb Cell 3(9):404

    Article PubMed PubMed Central  Google Scholar 

28. Crouch ML, Benchimol M, Alderete JF (2001) Binding of fibronectin byTrichomonas vaginalis is influenced by iron and calcium. Microb Pathog 31(3):131–144

    Article CAS PubMed  Google Scholar 

29. Figueroa-Angulo EE, Rendón-Gandarilla FJ, Puente-Rivera J, Calla-Choque JS, Cárdenas-Guerra RE, Ortega-López J et al (2012) The effects of environmental factors on the virulence ofTrichomonas vaginalis. Microbes Infect 14:1411–1427

    Article CAS PubMed  Google Scholar 

30. Torres-Romero JC, Arroyo R (2009) Responsiveness ofTrichomonas vaginalis to iron concentrations: evidence for a post-transcriptional iron regulation by an IRE/IRP-like system. Infect Genet Evol 9:1065–1074

    Article CAS PubMed  Google Scholar 

31. Krieger JN, Rein MF (1982) Zinc sensitivity of Trichomonas vaginalis: in vitro studies and clinical implications. J Infect Dis 146(3):341–345

    Article CAS PubMed  Google Scholar 

32. Vazquez Carrillo LI, Quintas Granados LI, Arroyo R, Mendoza Hernández G, González Robles A, Carvajal Gamez BI, Alvarez Sánchez ME (2011) The effect of Zn2+ on prostatic cell cytotoxicity caused byTrichomonas vaginalis. J Integr OMICS 1(2):198–210

    Google Scholar 

33. Garcia AF, Chang TH, Benchimol M, Klumpp DJ, Lehker MW, Alderete JF (2003) Iron and contact with host cells induce expression of adhesins on surface ofTrichomonas vaginalis. Mol Microbiol 47(5):1207–1224

    Article CAS PubMed PubMed Central  Google Scholar 

34. Moreno-Brito V, Yanez-Gomez C, Meza-Cervantez P, Avila-Gonzalez L, Rodriguez MA, Ortega-Lopez J, Gonzalez-Robles A, Arroyo R (2005) A trichomonas vaginalis 120 kDa protein with identity to hydrogenosome pyruvate:ferredoxin oxidoreductase is a surface adhesin induced by iron. Cell Microbiol 7:245–258

    Article CAS PubMed  Google Scholar 

35. Hernández-Gutiérrez R, Avila-González L, Ortega-López J, Cruz-Talonia F, Gómez-Gutierrez G, Arroyo R (2004) Trichomonas vaginalis: characterization of a 39-kDa cysteine proteinase found in patient vaginal secretions. Exp Parasitol 107(3):125–135

    Article PubMed  Google Scholar 

36. Ma L, Meng Q, Cheng W, Sung Y, Tang P, Hu S, Yu J (2011) Involvement of the GP63 protease in infection of Trichomonas vaginalis. Parasitol Res 109(1):71–79

    Article PubMed  Google Scholar 

37. Quan JH, Kang BH, Cha GH, Zhou W, Koh YB, Yang JB et al (2014) Trichonomas vaginalis metalloproteinase induces apoptosis of SiHa cells through disrupting the Mcl-1/Bim and Bcl-xL/Bim complexes. PLoS One 9(10):e110659

    Article PubMed PubMed Central  Google Scholar 

38. Quintas-Granados L, Villalpando J, Vázquez-Carrillo L, Arroyo R, Mendoza-Hernández G, Alvarez-Sánchez ME (2013) TvMP50 is an immunogenic metalloproteinase during male trichomoniasis. Mol Cell Proteomics 12:1953–1964

    Article PubMed PubMed Central  Google Scholar 

39. Carlton JM, Hirt RP, Silva JC, Delcher AL, Schatz M, Zhao Q et al (2007) Draft genome sequence of the sexually transmitted pathogenTrichomonas vaginalis. Science 315(5809):207–212

    Article PubMed PubMed Central  Google Scholar 

40. Dyall SD, Lester DC, Schneider RE, Delgadillo-Correa MG, Plümper E, Martinez A et al (2003)Trichomonas vaginalis Hmp35, a putative pore-forming hydrogenosomal membrane protein, can form a complex in yeast mitochondria. J Biol Chem 278(33):30548–30561

    Article CAS PubMed  Google Scholar 

41. Fernández-Martín KG, Alvarez-Sánchez ME, Arana-Argáez VE, Alvarez-Sánchez LC, Lara-Riegos JC, Torres-Romero JC (2017) Genome-wide identification, in silico characterization and expression analysis of ZIP-like genes fromTrichomonas vaginalis in response to zinc and iron. Biometals 30(5):663–675.https://doi.org/10.1007/s10534-017-0034-x

    Article PubMed  Google Scholar 

42. Conrad MD, Bradic M, Warring SD, Gorman AW, Carlton JM (2013) Getting trichy: tools and approaches to interrogatingTrichomonas vaginalis in a post-genome world. Trends Parasitol 29(1):17–25

    Article PubMed  Google Scholar 

43. Singh S, Singh G, Singh AK, Gautam G, Farmer R, Lodhi SS, Wadhwa G (2011) Prediction and analysis of paralogous proteins inTrichomonas vaginalis genome. Bioinformation 6:31–34

    Article PubMed PubMed Central  Google Scholar 

44. Leong IU, Stuckey A, Lai D, Skinner JR, Love DR (2015) Assessment of the predictive accuracy of five in silico prediction tools, alone or in combination, and two metaservers to classify long QT syndrome gene mutations. BMC Med Genet 16:34

    Article PubMed PubMed Central  Google Scholar 

45. Schultz J, Milpetz F, Bork P, Ponting CP (1998) SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci U S A 95(11):5857–5864

    Article CAS PubMed PubMed Central  Google Scholar 

46. Krogh A, Larsson B, Heijne G, Sonnhammer E (2001) Predicting transmembrane protein topology with a hidden markov model: application to complete genomes. J Mol Biol 305(3):567–580

    Article CAS PubMed  Google Scholar 

47. Buchan DWA, Minneci F, Nugent TCO, Bryson K, Jones DT (2013) Scalable web services for the PSIPRED protein analysis workbench. Nucleic Acids Res 41:W340–W348

    Article  Google Scholar 

48. Bailey TL, Boden M, Buske FA, Frith M, Grant CE, Clementi L, Ren J, Li WW, Noble WS (2009) MEME suite: tools for motif discovery and searching. Nucleic Acids Res 37(Web Server issue):W202–W208

    Article CAS PubMed PubMed Central  Google Scholar 

49. Gasteiger E, Hoogland C, Gattiker A, Duvaud S, Wilkins R, Appel RD, Bairoch A (2005) Protein identification and analysis tools on the ExPASy server. In: Walker JM (ed) The proteomics protocols handbook. Humana Press, Totowa, NJ, pp 571–607

    Chapter  Google Scholar 

50. Yu CS, Chen YC, Lu CH, Hwang JK (2006) Prediction of protein subcellular localization. Proteins 64:643–651

    Article CAS PubMed  Google Scholar 

51. Rogers EE, Eide DJ, Guerinot ML (2000) Altered selectivity in an Arabidopsis metal transporter. Proc Natl Acad Sci U S A 97:12356–12360

    Article CAS PubMed PubMed Central  Google Scholar 

52. Huang L, Tepaamorndech S (2013) The SLC30 family of zinc transporters - a review of current understanding of their biological and pathophysiological roles. Mol Asp Med 34(2-3):548–560

    Article CAS  Google Scholar 

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