- Rafael Berenguer-Vidal11,
- Rafael Verdú-Monedero12,
- Juan Morales-Sánchez12,
- Inmaculada Sellés-Navarro13 &
- …
- Oleksandr Kovalyk12
Part of the book series:Lecture Notes in Computer Science ((LNCS,volume 13258))
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Abstract
One of the main diseases that affect to the optic nerve is glaucoma, which causes progressive and irreversible damage that reduces the vision field of the patient. The thickness of the retinal nerve fiber layer is an indicator of the status and progression of this illness. A line of research in the early diagnosis of glaucoma is based on the analysis of the asymmetry between the morphological characteristics of both eyes. This article presents preliminary results that start from this hypothesis and use the relative absolute difference between the thickness of the RNFL in both eyes of the same patient as a characteristic of asymmetry. Results indicate that there is a significant difference in the mean value of the asymmetry between healthy patients and those with glaucoma. As future work, the inclusion of automatic methods for the measurement of the RNFL thickness and the use of classification techniques based on these characteristics of asymmetry for the early diagnosis of glaucoma will be developed.
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Acknowledgments
This work has been partially supported by Spanish National projects AES2017-PI17/00771, AES2017-PI17/00821 (Instituto de Salud Carlos III), and Regional project 20901/PI/18 (Fundación Séneca).
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Authors and Affiliations
Universidad Católica San Antonio, 30107, Murcia, Spain
Rafael Berenguer-Vidal
Universidad Politécnica de Cartagena, 30202, Cartagena, Spain
Rafael Verdú-Monedero, Juan Morales-Sánchez & Oleksandr Kovalyk
Hospital General Universitario Reina Sofía, 30003, Murcia, Spain
Inmaculada Sellés-Navarro
- Rafael Berenguer-Vidal
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- Rafael Verdú-Monedero
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- Juan Morales-Sánchez
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- Inmaculada Sellés-Navarro
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- Oleksandr Kovalyk
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Correspondence toRafael Berenguer-Vidal.
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Universidad Politécnica de Cartagena, Cartagena, Spain
José Manuel Ferrández Vicente
Universidad Nacional de Educación a Distancia, Madrid, Spain
José Ramón Álvarez-Sánchez
Universidad Nacional de Educación a Distancia, Madrid, Spain
Félix de la Paz López
Ohio State University, Columbus, OH, USA
Hojjat Adeli
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Berenguer-Vidal, R., Verdú-Monedero, R., Morales-Sánchez, J., Sellés-Navarro, I., Kovalyk, O. (2022). Analysis of the Asymmetry in RNFL Thickness Using Spectralis OCT Measurements in Healthy and Glaucoma Patients. In: Ferrández Vicente, J.M., Álvarez-Sánchez, J.R., de la Paz López, F., Adeli, H. (eds) Artificial Intelligence in Neuroscience: Affective Analysis and Health Applications. IWINAC 2022. Lecture Notes in Computer Science, vol 13258. Springer, Cham. https://doi.org/10.1007/978-3-031-06242-1_50
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