It covers several areas of statistics. The courses do not care about purely mathematical details like formula derivation and strict proofs. The main focus of the specialisation is an analysis of large datasets with programmatic methods.

For beginners:

R is not properly introduced, so it might be hard to grasp it without prior programming experience. No prior mathematical background is required.

For experienced:

It is a lovely way to update personal analytical skills. The final peer-reviewed reports might be unexpected complications since they require a sufficient amount of academic writing.

Statistics with R Specialization on Coursera