| År | Modtager/nomineret arbejde | Pris | Resultat |
|---|
|
| 1989 | The Lion and the Cobra | Grammy Award for Best Female Rock Vocal Performance | Nomineret[13] |
| 1990 | Sinéad O'Connor | Rockbjornen for Best Foreign Artist | Vundet[14] |
| Billboard Music Awards for Rock Female Artist | Vundet[15] |
| "Nothing Compares 2 U" | Billboard Music Awards for No.1 World Single | Vundet[15] |
| MTV Video Music Award for Video of the Year | Vundet |
| MTV Video Music Award for Best Female Video | Vundet |
| MTV Video Music Award for Best Post-Modern Video | Vundet |
| MTV Video Music Award for Breakthrough Video | Nomineret |
| MTV Video Music Award for Viewer's Choice | Nomineret |
| MTV Video Music Award for International Viewer's Choice (MTV Europe) | Nomineret |
| 1991 | Grammy Award for Record of the Year | Nomineret |
| Grammy Award for Best Female Pop Vocal Performance | Nomineret |
| Grammy Award for Best Music Video, Short Form | Nomineret |
| I Do Not Want What I Haven't Got | Grammy Award for Best Alternative Music Performance | Vundet[16] |
| Juno Awards for International Album of the Year | Nomineret |
| Sinéad O'Connor | Juno Awards for International Entertainer of the Year | Nomineret |
| American Music Award for Favorite Pop/Rock Female Artist | Nomineret |
| Brit Award for International Female Solo Artist | Vundet |
| Danish Music Awards for Foreign Female Artist of the Year | Vundet |
| "Nothing Compares 2 U" | Danish Music Awards Foreign Hit of the Year | Vundet |
| 1992 | Year of the Horse | Grammy Award for Best Music Video, Long Form | Nomineret[17] |
| 1994 | "You Made Me the Thief of Your Heart" | MTV Video Music Award for Best Video from a Film | Nomineret |
| Sinéad O'Connor | Goldene Europa Awards for Best International Singer | Vundet |
| Žebřík Music Award for Best International Female[18] | Nomineret |
| 1995 | Brit Award for International Female Solo Artist | Nomineret |
| 1996 | "Famine" | Grammy Award for Best Music Video, Short Form | Nomineret |
| D&AD Award for Pop Promo Video (Individual) | Wood Pencil |
| 2000 | "No Man's Woman" | Billboard Music Video Award for Best Jazz/AC Clip of the Year | Nomineret |
| Sinéad O'Connor | Žebřík Music Award for Best International Female[19] | Nomineret |
| 2003 | "Troy" | International Dance Music Awards for Best Progressive House/Trance Track | Nomineret |
| "Tears from the Moon" | Nomineret |
| 2004 | Sinéad O'Connor | Meteor Music Awards for Best Irish Female | Nomineret |
| 2005 | Nomineret |
| 2006 | Nomineret |
| 2007 | Nomineret |
| 2008 | Nomineret |
| 2012 | "Lay Your Head Down" | World Soundtrack Award for Best Original Song Written Directly for a Film | Vundet |
| Golden Globe Award for Best Original Song | Nomineret[20] |
| "Queen of Denmark" | Rober Awards Music Poll for Best Cover Version | Nomineret |
| 2013 | "GMF" (withJohn Grant) | Rober Awards Music Poll for Song of the Year | Nomineret |
| 2015 | I'm Not Bossy, I'm the Boss | Meteor Choice Music Prize for Best Album | Nomineret[21] |
| "Take Me To Church" | Meteor Choice Music Prize for Song of the Year | Nomineret[22] |
| 2023 | I Do Not Want What I Haven't Got | Choice Music Prize 'Classic Irish Album' | Vundet[23][24] |