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Wicipedia
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SOCS2

Oddi ar Wicipedia
SOCS2
Strwythurau
PDBHuman UniProt search:PDBeRCSB
Rhestr o ddynodwyr PDB

2C9W,4JGH,5BO4

Dynodwyr
CyfenwauSOCS2, CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2, suppressor of cytokine signaling 2
Dynodwyr allanolOMIM:605117HomoloGene:2880GeneCards:SOCS2
PatrwmRNA pattern


Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaiddinsulin-like growth factor receptor binding
protein kinase inhibitor activity
JAK pathway signal transduction adaptor activity
GO:0001948, GO:0016582 protein binding
growth hormone receptor binding
1-phosphatidylinositol-3-kinase regulator activity
Cydrannau o'r gellcytoplasm
cytosol
phosphatidylinositol 3-kinase complex
Prosesau biolegolreceptor signaling pathway via JAK-STAT
response to estradiol
GO:0007243 intracellular signal transduction
negative regulation of protein kinase activity
cytokine-mediated signaling pathway
negative regulation of apoptotic process
GO:1903105 negative regulation of insulin receptor signaling pathway
cellular response to hormone stimulus
growth hormone receptor signaling pathway
regulation of signal transduction
regulation of cell growth
protein ubiquitination
regulation of growth
negative regulation of signal transduction
negative regulation of receptor signaling pathway via JAK-STAT
positive regulation of signal transduction
lactation
regulation of multicellular organism growth
negative regulation of multicellular organism growth
post-translational protein modification
positive regulation of neuron differentiation
mammary gland alveolus development
interleukin-7-mediated signaling pathway
regulation of phosphatidylinositol 3-kinase activity
phosphatidylinositol phosphate biosynthetic process
Sources:Amigo /QuickGO
Orthologau
SpeciesBod dynolLlygoden
Entrez

8835

n/a

Ensembl

ENSG00000120833

n/a

UniProt

O14508

n/a

RefSeq (mRNA)
NM_001270467
NM_001270468
NM_001270469
NM_001270470
NM_001270471

NM_003877

n/a

RefSeq (protein)
NP_001257396
NP_001257397
NP_001257398
NP_001257399
NP_001257400

NP_003868

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynSOCS2 ywSOCS2 a elwir hefyd ynSuppressor of cytokine signaling 2 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q22.[2]

Cyfystyron

[golygu |golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SOCS2.

  • CIS2
  • SSI2
  • Cish2
  • SSI-2
  • SOCS-2
  • STATI2

Llyfryddiaeth

[golygu |golygu cod]
  • "Suppressor of Cytokine Signaling-2 (SOCS2) Regulates the Microglial Response and Improves Functional Outcome after Traumatic Brain Injury in Mice.". PLoS One. 2016. PMID 27071013.
  • "SOCS2: physiological and pathological functions.". Front Biosci (Elite Ed). 2016. PMID 26709655.
  • "A herpes simplex virus type 2-encoded microRNA promotes tumor cell metastasis by targeting suppressor of cytokine signaling 2 in lung cancer.". Tumour Biol. 2017. PMID 28468588.
  • "GLP-1 analogue recovers impaired insulin secretion from human islets treated with palmitate via down-regulation of SOCS2.". Mol Cell Endocrinol. 2017. PMID 27566229.
  • "The suppressor of cytokine signaling 2 (SOCS2) inhibits tumor metastasis in hepatocellular carcinoma.". Tumour Biol. 2016. PMID 27465557.

Cyfeiriadau

[golygu |golygu cod]
  1. "Human PubMed Reference:".
  2. SOCS2 - Cronfa NCBI
Wedi dod o "https://cy.wikipedia.org/w/index.php?title=SOCS2&oldid=4497974"
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