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Neidio i'r cynnwys
Wicipedia
Chwilio

SNRPB

Oddi ar Wicipedia
SNRPB
Strwythurau
PDBHuman UniProt search:PDBeRCSB
Rhestr o ddynodwyr PDB

1D3B,3CW1,3PGW,4PJO,4WZJ,3JCR

Dynodwyr
CyfenwauSNRPB, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B, CCMS, small nuclear ribonucleoprotein polypeptides B and B1
Dynodwyr allanolOMIM:182282HomoloGene:134543GeneCards:SNRPB
PatrwmRNA pattern


Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaiddhistone pre-mRNA DCP binding
U2 snRNA binding
GO:0001948, GO:0016582 protein binding
telomerase RNA binding
RNA binding
U1 snRNP binding
U2 snRNP binding
Cydrannau o'r gellcytoplasm
SMN-Sm protein complex
cytosol
catalytic step 2 spliceosome
U4/U6 x U5 tri-snRNP complex
histone pre-mRNA 3'end processing complex
U5 snRNP
U12-type spliceosomal complex
U2 snRNP
U1 snRNP
methylosome
U7 snRNP
small nuclear ribonucleoprotein complex
telomerase holoenzyme complex
spliceosomal complex
U4 snRNP
extracellular exosome
U2-type prespliceosome
cnewyllyn cell
nucleoplasm
U2-type precatalytic spliceosome
U2-type catalytic step 2 spliceosome
Prosesau biolegolmRNA splicing, via spliceosome
termination of RNA polymerase II transcription
mRNA processing
spliceosomal snRNP assembly
RNA splicing
histone mRNA metabolic process
protein methylation
import into nucleus
brain development
Sources:Amigo /QuickGO
Orthologau
SpeciesBod dynolLlygoden
Entrez

6628

n/a

Ensembl

ENSG00000125835

n/a

UniProt

P14678

n/a

RefSeq (mRNA)

NM_198216
NM_003091

n/a

RefSeq (protein)

NP_003082
NP_937859

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynSNRPB ywSNRPB a elwir hefyd ynSmall nuclear ribonucleoprotein polypeptides B and B1 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p13.[2]

Cyfystyron

[golygu |golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNRPB.

  • COD
  • CCMS
  • SNRPB1
  • SmB/B'
  • Sm-B/B'
  • snRNP-B
  • SmB/SmB'

Llyfryddiaeth

[golygu |golygu cod]
  • "Disrupted auto-regulation of the spliceosomal gene SNRPB causes cerebro-costo-mandibular syndrome.". Nat Commun. 2014. PMID 25047197.
  • "Spliceosomal UsnRNP biogenesis, structure and function.". Curr Opin Cell Biol. 2001. PMID 11343899.
  • "Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.". Genome Biol. 2016. PMID 27287018.
  • "Cerebro-costo-mandibular syndrome: Clinical, radiological, and genetic findings.". Am J Med Genet A. 2016. PMID 26971886.
  • "Mutations in SNRPB, encoding components of the core splicing machinery, cause cerebro-costo-mandibular syndrome.". Hum Mutat. 2015. PMID 25504470.

Cyfeiriadau

[golygu |golygu cod]
  1. "Human PubMed Reference:".
  2. SNRPB - Cronfa NCBI
Wedi dod o "https://cy.wikipedia.org/w/index.php?title=SNRPB&oldid=4497962"
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