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Wicipedia
Chwilio

MXD1

Oddi ar Wicipedia
MXD1
Strwythurau
PDBHuman UniProt search:PDBeRCSB
Rhestr o ddynodwyr PDB

1E91,1G1E,1NLW,1PD7,1S5Q

Dynodwyr
CyfenwauMXD1, BHLHC58, MAD, MAD1, MAX dimerization protein 1
Dynodwyr allanolOMIM:600021HomoloGene:1767GeneCards:MXD1
PatrwmRNA pattern
Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaiddGO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA binding
GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001948, GO:0016582 protein binding
GO:0001104 transcription coregulator activity
protein dimerization activity
GO:0001106 transcription corepressor activity
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Cydrannau o'r gellcnewyllyn cell
nucleoplasm
mitocondria
cytosol
Prosesau biolegolmulticellular organism development
cell population proliferation
GO:0009373 regulation of transcription, DNA-templated
GO:1901227 negative regulation of transcription by RNA polymerase II
transcription, DNA-templated
Sources:Amigo /QuickGO
Orthologau
SpeciesBod dynolLlygoden
Entrez

4084

n/a

Ensembl

ENSG00000059728

n/a

UniProt

Q05195

n/a

RefSeq (mRNA)

NM_002357
NM_001202513
NM_001202514

n/a

RefSeq (protein)

NP_001189442
NP_001189443
NP_002348

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynMXD1 ywMXD1 a elwir hefyd ynMAX dimerization protein 1 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p13.3.[2]

Cyfystyron

[golygu |golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MXD1.

  • MAD
  • MAD1
  • BHLHC58

Llyfryddiaeth

[golygu |golygu cod]
  • "Effect of the transcriptional repressor Mad1 on proliferation of human melanoma cells.". Exp Dermatol. 2002. PMID 12366697.
  • "Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25.". Genomics. 1994. PMID 7829091.
  • "miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of MXD1.". Stem Cells Dev. 2016. PMID 27520398.
  • "TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction.". BMB Rep. 2016. PMID 26698869.
  • "The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.". Mol Carcinog. 2009. PMID 19526459.

Cyfeiriadau

[golygu |golygu cod]
  1. "Human PubMed Reference:".
  2. MXD1 - Cronfa NCBI
Wedi dod o "https://cy.wikipedia.org/w/index.php?title=MXD1&oldid=5435075"
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